Chifukwa Chiyani Timafunikira Mankhwala Ogwira Ntchito?

• Gulu lathu likukumana ndi kuwonjezeka kwakukulu kwa chiwerengero cha anthu omwe akudwala matenda ovuta, osatha�monga matenda a shuga, mtima, khansa, matenda amisala, matenda a autoimmune monga nyamakazi.
• Dongosolo lamankhwala lochitidwa ndi madokotala ambiri limatsata chithandizo chamankhwala mwachangu,�matenda ndi chithandizo cha kuvulala kapena matenda omwe ndi anthawi yochepa komanso akufunika chisamaliro chachangu, monga appendicitis kapena kuthyoka mwendo. Madokotala amagwiritsira ntchito mankhwala achindunji, oikidwa monga mankhwala kapena opaleshoni imene cholinga chake ndi kuchiza vuto kapena chizindikiro chaposachedwapa.
• Tsoka ilo, njira yosamalira odwala kwambiri ilibe njira yoyenera komanso zida zopewera ndi kuchiza matenda ovuta, osatha.�Nthawi zambiri sizimaganizira za mpangidwe wapadera wa majini wa munthu aliyense kapena zinthu monga kukhudzidwa kwa chilengedwe ku poizoni ndi mbali za moyo wamasiku ano zomwe zimakhudza mwachindunji kukwera kwa matenda osatha m'magulu amakono a Kumadzulo.
• Pali kusiyana kwakukulu pakati pa kafukufuku ndi momwe madokotala amachitira.�Kusiyana pakati pa kafukufuku yemwe akubwera mu sayansi yoyambira ndi kuphatikizika muzachipatala ndi wamkulu - utali wazaka 50 - makamaka pankhani ya matenda ovuta, osatha.
• Madokotala ambiri sanaphunzitsidwe mokwanira kuti awone zomwe zimayambitsa�Matenda ovuta, osatha komanso kugwiritsa ntchito njira monga zakudya, zakudya, ndi masewera olimbitsa thupi pochiza ndi kupewa matendawa mwa odwala awo.

Kodi Functional Medicine imasiyana bwanji?

Mankhwala ogwira ntchito amaphatikizapo kumvetsa�chiyambi, kupewa, ndi chithandizo�matenda ovuta, osatha. Zizindikiro za njira yogwiritsira ntchito mankhwala ndizo:

• Chisamaliro chokhazikika kwa odwala.�Cholinga cha mankhwala ogwira ntchito ndi chisamaliro cha odwala, kulimbikitsa thanzi ngati moyo wabwino, kupitirira kusakhalapo kwa matenda. Pomvetsera wodwala ndi kuphunzira nkhani yake, dokotalayo amabweretsa wodwalayo mu njira yodziwira ndikukonza chithandizo chomwe chimakwaniritsa zosowa zapadera za munthuyo.
• Njira yophatikizira, yozikidwa ndi sayansi yazaumoyo.�Ogwira ntchito zachipatala amayang'ana "kumtunda" kuti aganizire zovuta zomwe zimachitika m'mbiri ya wodwalayo, physiology, ndi moyo zomwe zingayambitse matenda. Mapangidwe apadera a majini a wodwala aliyense amaganiziridwa, pamodzi ndi zonse zamkati (maganizo, thupi, ndi mzimu) ndi zakunja (zakuthupi ndi zamagulu) zomwe zimakhudza kugwira ntchito kwathunthu.
• Kuphatikiza njira zabwino zachipatala.�Mankhwala ogwira ntchito amaphatikiza njira zachipatala zaku Western ndi mankhwala omwe nthawi zina amatchedwa �njira ina� kapena �ophatikizana�, kupanga chidwi cha kupewa kudzera muzakudya, zakudya, ndi masewera olimbitsa thupi; kugwiritsa ntchito kuyezetsa kwaposachedwa kwa labotale ndi njira zina zowunikira; ndi mankhwala ophatikizika ndi/kapena botanical mankhwala, zowonjezera, zakudya achire, mapulogalamu detoxification, kapena njira zothetsera nkhawa.

Mankhwala ogwira ntchito ndi oposa njira yosiyana ya chithandizo chamankhwala, ndi nzeru yosiyana kwambiri ndi momwe tonsefe timaperekera komanso kudya chithandizo chamankhwala.� Ndikhoza kunena moona mtima kuti m'zochita zanga, sindichiza matenda, koma ndimathandizira odwala; ena omwe ali ndi matenda ndipo ena alibe. � Ndimayang'ana kwambiri kukhazikika kwa physiology ndikubwezeretsa magwiridwe antchito athanzi kudzera muzakudya komanso kusintha kwa moyo.

Anthu nthawi zambiri amakhala ndi zizindikiro zazikulu ndipo amadwala, koma samakwaniritsa zofunikira zaumisiri wa matenda enaake.� M'maofesi ambiri izi zikutanthauza kuti samalandila chithandizo nkomwe, koma kwa odwala anga, izi ndizovuta chabe. kuyambira.� Ndimagwira ntchito ndi odwala anga kuti ndipeze zovuta zomwe zimatsogolera kuzizindikiro zawo, kenako ndikupanga njira zowongolera izi ndikubwezeretsa thanzi labwino. �

Njira yothandizira mankhwala ochizira matenda osachiritsika ndi yomwe siinakhazikike pa wothandizila m'modzi kapena njira ngati njira yochizira kapena yothandizira. Zimakhazikika pa mfundo yakuti kubwezeretsedwa kwa kagayidwe kake ka maselo, kupyolera mu kuchepetsa kuchuluka kwa poizoni ndi kupsyinjika kwa okosijeni m'thupi, kudzalola kupuma kwa mitochondrial, kupanga mphamvu zamagetsi, ndipo pamapeto pake kuchepetsa zizindikiro ndi zizindikiro za matenda aakulu. . Ngakhale madotolo ambiri okonda zakudya amazindikira kuti njira zothandizira zakudya zopatsa thanzi zokha ndizothandiza kwambiri kwa odwala omwe ali ndi matenda ang'onoang'ono kapena ocheperako, milandu yowopsa nthawi zambiri imafunikira njira yogwira ntchito bwino.

Lingaliro lamankhwala logwira ntchito ndi njira yoyambira idapangidwa kuti igwiritsidwe ntchito pachipatala kwa odwala kutopa kwambiri omwe amakhala ndi zotsatira zabwino kwambiri, ndipo chifukwa chodziwika bwino m'matenda ambiri osachiritsika, akhala akugwiritsidwa ntchito kwazaka zambiri m'mavuto ena mopambana kwambiri, kuphatikiza fibromyalgia, nyamakazi ya nyamakazi. , ndi matenda a autoimmune.^1-8 Ntchito yomaliza ya Bland, Rigden, Cheney, ndi ena pochiza matenda otopa kwambiri yakhala ngati template yopambana, ndipo njira iyi tsopano ikugwiritsidwa ntchito pochiza matenda osiyanasiyana osatha.^1-7.

Filosofi yogwira ntchito yamankhwala imakhazikika pamalingaliro akuti kuwonongeka kwa matumbo am'mimba chifukwa chodya zakudya ndi poizoni wamadzi, komanso kugwiritsa ntchito mankhwala omwe amaperekedwa ndi mankhwala omwe amagulitsidwa (monga maantibayotiki ndi NSAIDS). kumayambitsa dysbiosis ndi hyperpermeable mucosa m'matumbo, kapena leaky gut syndrome. M'mimba hyperpermeablity izi zingachititse kuti matumbo mucosa kulephera kukhala chotchinga kusankha, kutsogolera kuwoloka kwa poizoni chakudya ndi pang'ono digested chakudya mapuloteni kudzera matumbo mucosa ndi mu zokhudza zonse magazi. Zotsatira zake ndikuwonjezeka kwa ziwengo zazakudya komanso kuchuluka kwapoizoni. (onani Chithunzi 1).

Kuwonjezeka kwapoizoni kumeneku kumatha, pakapita nthawi, kumayambitsa kupsinjika kwachiwindi komanso kuthekera kwake kochotsa zinthu izi mokwanira kudzera munjira za gawo I ndi II. Izi pamapeto pake zidzapangitsa kuwonjezereka kwa kawopsedwe ka minofu ya systemic.

Kuwonjezeka kwa kawopsedwe ka minofu kumaganiziridwa kuti ndizomwe zimayambitsa vuto la mitochondrial, zomwe zimapangitsa kuti ma cell a thupi, kuphatikiza maselo a minofu, asamagwiritse ntchito bwino njira zotengera mpweya wa aerobic metabolic. Izi ndizomwe zimapangitsa kuti ATP ambiri apangidwe. Kuchepa kwa kupanga kwa ATP kwa ma cell kumatha kuwerengera zambiri (ngati sizinthu zonse) zazizindikiro ndi zizindikiro zomwe zimagwirizanitsidwa ndi matenda ambiri osatha, monga matenda otopa kwambiri (CFS) ndi fibromyalgia (FMS).

Kuchulukitsidwa kwamatumbo am'matumbo kumatha kupangitsanso kuti mapuloteni omwe amagayidwa pang'ono kapena akulu alowe m'magazi ndikukhala ngati ma antigen. Zotsatira za antigen-antibody complexes zikuwoneka kuti zimakhala ndi mgwirizano wa synovium of articulations, Izi zimabweretsa kuyankha kotupa m'mizere yolumikizana yomwe imawoneka mu nyamakazi monga nyamakazi ya nyamakazi (RA). Mankhwala akuluakulu omwe amagwiritsidwa ntchito poyamba ndi madokotala odziwika bwino pochiza RA ndi (zodabwitsa) NSAIDs. NSAIDs, malinga ndi PDR, zimabweretsa kuwonjezeka kwa m'mimba. Kodi ndizotheka kuti chithandizo chachikhalidwe cha allopathic cha nyamakazi changopangitsa kuti wodwalayo azimva ululu, pomwe akukulitsa matendawa?

Njira yochiritsira yamankhwala, motero, imayang'ana pokonza matumbo a m'mimba, kukonza matumbo a dysbiosis, kupereka zinthu m'thupi kuti zithandizire kutulutsa minofu, kuchepetsa kupsinjika kwa okosijeni, ndipo pamapeto pake kulimbikitsa kubwereranso kwa ma cell metabolism. Kuunika kumayamba ndikuzindikira thanzi la m'mimba komanso momwe chiwindi chimagwirira ntchito komanso kuthekera kwake kochotsa poizoni. Izi zimachitika mothandizidwa ndi mafunso azizindikiro za odwala, monga mafunso owunikira kagayidwe kachakudya ndi maphunziro a labotale ogwira ntchito, monga vuto la lactulose/mannitol powunika kuchuluka kwa matumbo, komanso kusanthula kwathunthu kwa digestive stool (CDSA) pozindikira zizindikiro za chimbudzi. , kuyamwa, ndi zomera za m'matumbo. Kuthekera kwa chiwindi cha detoxification kumatha kuyesedwa pogwiritsa ntchito mayeso a caffeine clearance ndi conjugation metabolite Challenge test, omwe amayesa gawo I (cytochrome P450) ndi gawo II (conjugation) njira zochotsera chiwindi.onani Chithunzi 2). Mayesowa samachitidwa ndi ma laboratories anthawi zonse azachipatala, koma amapezeka kudzera m'ma laboratories apadera omwe amayesa ntchito.⁹

Deta ikasonkhanitsidwa, pulogalamu yamankhwala (onani Chithunzi 3) amasankhidwa, omwe angaphatikizepo zakudya zapadera kuti akonze vuto lililonse la m'mimba (leaky gut syndrome). Zakudya zapayekha monga L-glutamine, mapuloteni oyeretsedwa a hypoallergenic mpunga, inulin, pantothenic acid, ndi ma antioxidants atha kugwiritsidwa ntchito, komabe, chakudya chamankhwala.^10,11 nthawi zambiri zimakhala zosavuta komanso zothandiza kugwiritsa ntchito kuchipatala. Kuvuta kwa chimbudzi ndi kuyamwa komwe kumaperekedwa pa CDSA kumatha kuthandizidwa ndikugwiritsa ntchito kwakanthawi kwa ma pancreatic enzymes ndi HCL (ngati zikuwonetsedwa) kwa odwala omwe alibe gastritis kapena zilonda zam'mimba. Dysbiosis, mawu omwe amagwiritsidwa ntchito pofotokoza kusalinganika kwa zomera za colonic, akhoza kuyankhidwa ndi kayendetsedwe ka lactobacillus acidophilus ndi ma probiotics monga fructooligosaccharides (FOS).

Mabakiteriya aliwonse a pathogenic, yisiti, kapena tizilombo tomwe tapezeka pa CDSA tikuyenera kuthandizidwa ndi mankhwala (kapena achilengedwe) omwe amaperekedwa ndi mayeso a CDSA. Izi zingaphatikizepo zinthu zomwe sizinalembedwe monga berberine, adyo, nyemba za citrus, artemisia, uva ursi, ndi zina. Pulogalamuyi yobwezeretsa matumbo imafotokozedwa ndi Bland, Rigden, Cheney, ndi ena ngati njira ya "Four R".^3-4.

Njira ya "Four R" yobwezeretsanso m'mimba

Chotsani: Chotsani tizilombo toyambitsa matenda, yisiti ndi/kapena tizilombo toyambitsa matenda ndi mankhwala achilengedwe kapena mankhwala omwe aperekedwa pa CDSA (ie, berberine/goldenseal, adyo, artemesia, njere za citrus, uva ursi, etc.).

Chotsani zakudya zomwe zimadziwika kuti allergenic ndi/kapena kutsatira zakudya zosinthidwa popewa zakudya zamkaka ndi gilateni, ndikugogomezera zakudya zatsopano zosakonzedwa.

Bwezerani: Perekani ma pancreatic multidigestive enzymes ndi HCL ngati kuli koyenera, makamaka ngati zolembera za malabsorption zilipo pa CDSA.

Renoculate: Onjezani lactobacillus acidophilus, bifidobacteria ndi ma probiotics monga fructooligosaccharides (FOS) ndi inulin.

Kukonzekera: Perekani zakudya zothandizira m'mimba mucosal umphumphu, monga L-glutamine, antioxidants, glutathione, N-acetylcysteine ​​(NAC), zinc, pantothenic acid, medium chain triglycerides (MCTs), fiber, etc.

Pambuyo pokonza matumbo a m'mimba, kupititsa patsogolo njira zowonongeka kwa chiwindi zingatheke popereka zakudya zomwe zimagwiritsidwa ntchito mu gawo loyamba la biotransformation ndi gawo lachiwiri la conjugation pathways. Izi zingaphatikizepo zakudya monga N-acetyl cysteine, methionine, cysteine, glycine, glutamic acid, glutathione ndi antioxidant zakudya (onani Chithunzi 3). Komabe, kugwiritsa ntchito mankhwala opangidwa mwapadera ndi othandiza kwambiri komanso osavuta kugwiritsa ntchito pachipatala.

Odwala omwe ali ndi gawo lokwezeka la gawo loyamba la cytochrome P450 enzyme komanso pang'onopang'ono gawo lachiwiri lolumikizana ayenera kuthandizidwa ndi mankhwala oletsa antioxidant asanayambe kutulutsa poizoni. Izi zimachepetsa kupanga mamolekyu apakati akupha omwe amawonjezera kupsinjika kwa okosijeni m'thupi.

Izi ziyenera kuphatikizidwa ndi zakudya zomwe zimagogomezera zakudya zatsopano, ndikuchotsa zakudya zopangidwa ndi allergenic. Izi zidzachepetsa odwala omwe ali ndi poizoni wambiri (exotoxins), pamene pulogalamu ya m'mimba idzachepetsa poizoni wochokera m'mimba (endotoxins). Kutsatira zakudya zosinthidwa zomwe zimathetsa kuyamwa kwa gilateni ndi mkaka wokhala ndi zakudya, ndikusiya mankhwala ambiri momwe mungathere, kungathandizenso panthawi ya detoxification.

Zothandizira

1. Bland J, Bralley A: Kukula kwa thanzi la ma enzymes a hepatic detoxification, J Appl Nutr 44, 1992.
2. Rigden S: Kafukufuku wofufuza-CFIDS lipoti loyambirira la kafukufuku: Kupititsa patsogolo Kuzindikira ndi Kuchiza kwa Odwala Matendawa, 1991, Seattle.
3. Rigden S: Enterohepatic resuscitation program ya CFIDS, Mbiri ya CFIDS Spring, 1995.
4. Cheney PR, Lapp CW: Kutsitsimula kwa Entero-hepatic kwa odwala omwe ali ndi matenda otopa kwambiri: piramidi ya zakudya zopatsa thanzi, Mbiri ya CFIDS Chaka, 1993.
5. Lanfranchi RG, et al: Fibromyalgia, kupweteka kosatha ndi leaky gut syndrome. Chiropr wamasiku ano, March/April: 32-9, 1994.
6. Rowe AH: Kutopa kwamthupi ndi toxemia, Ann Allergy 17:9-18, 1959 .
7. Pressman AH: Kuopsa kwa metabolic ndi ululu wa neuromuscular, matenda olumikizana, ndi fibromyalgia, J Am Chiropr Assoc Sept: 77-78, 1993.
8. Gantz NM, Holmes GP: Chithandizo cha odwala omwe ali ndi matenda otopa kwambiri, mankhwala 36(6):855-862, 1989.
9. Labu Yofufuza Zazikulu Zakusuta: 63 Zillicoa St, Ashville, NC 28801, 1-704-253-0621, www.gsdl.com.
10. HealthComm International, Inc., Functional Medicine Research Center, PO Box 1729, Gig Harbor, WA 98335, 1-800-843- 9660, www.healthcomm.com.
11. Metagenics, Inc., 971 Calle Negocio, San Clemente, CA 92673, 1-800-692-9400.

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