Back Clinic Gastro Intestinal Health Functional Medicine Team. Kapepala ka m'mimba kapena (GI) amachita zambiri kuposa kugaya chakudya. Zimathandizira ku machitidwe osiyanasiyana a thupi ndi ntchito. Dr. Jimenez akuyang'ana njira zomwe zapangidwa kuti zithandizire kuthandizira thanzi la thirakiti la GI ndi ntchito, komanso kulimbikitsa kusinthasintha kwa tizilombo toyambitsa matenda. Kafukufuku akuwonetsa kuti 1 mwa anthu anayi ku US ali ndi vuto la m'mimba kapena matumbo lomwe ndi lalikulu kwambiri lomwe limasokoneza zochita zawo zatsiku ndi tsiku komanso moyo wawo.
Matenda a m'mimba kapena chimbudzi amatchulidwa kuti Matenda a M'mimba (kapena GI). Cholinga ndikukwaniritsa bwino m'mimba. Pamene dongosolo la m'mimba likugwira ntchito bwino, munthu amanenedwa kuti ali ndi thanzi labwino. Thirakiti la GI limateteza thupi pochotsa poizoni osiyanasiyana ndikuchita nawo njira zoteteza chitetezo chathupi kapena chitetezo chamthupi chikalumikizana ndi ma antibodies ndi ma antigen. Izi pamodzi ndi kuthandizira chimbudzi ndi kuyamwa kwa zakudya kuchokera ku zakudya za munthu.
Kwa anthu omwe akukumana ndi kudzimbidwa kosalekeza chifukwa cha mankhwala, kupsinjika maganizo, kapena kusowa kwa fiber, kodi masewera olimbitsa thupi angathandize kulimbikitsa kuyenda kwamatumbo nthawi zonse?
Kuyenda Chifukwa Chothandizira Kudzimbidwa
Kudzimbidwa ndi vuto wamba. Kukhala kwambiri, kumwa mankhwala, kupsinjika maganizo, kapena kusapeza ulusi wokwanira kungayambitse kusayenda kwamatumbo pafupipafupi. Kusintha kwa moyo kumatha kuwongolera nthawi zambiri. Imodzi mwa njira zothandiza kwambiri ndikuphatikizira kuchita masewera olimbitsa thupi nthawi zonse, kulimbikitsa matumbo kuti agwire mwachibadwa (Huang, R., et al., 2014). Izi zikuphatikizapo kuthamanga, yoga, madzi aerobics, ndi mphamvu kapena kuyenda mofulumira kuti muchepetse kudzimbidwa.
Kafukufuku
Kafukufuku wowunikira amayi azaka zapakati onenepa omwe anali ndi kudzimbidwa kosatha kwa milungu 12. (Tantawy, SA, et al., 2017)
Gulu loyamba linkayenda pa treadmill katatu pa sabata kwa mphindi 3.
Gulu lachiwiri silinachite zolimbitsa thupi.
Gulu loyamba linali ndi kusintha kwakukulu kwa zizindikiro zawo za kudzimbidwa komanso kuunika kwa moyo.
Kusalinganika kwa bakiteriya m'matumbo kumalumikizidwanso ndi vuto la kudzimbidwa. Kafukufuku wina adayang'ana kwambiri za momwe kuyenda mwachangu ndi masewera olimbitsa thupi kumalimbitsa minofu yapakati ngati matabwa pamapangidwe amatumbo a microbiota. (Morita, E., et al., 2019) Zotsatira zinasonyeza kuti masewera olimbitsa thupi monga mphamvu / kuyenda mofulumira kungathandize kuwonjezera matumbo Matenda a Bacteroides, mbali yofunika kwambiri ya mabakiteriya abwino m'matumbo. Kafukufuku wawonetsa zotsatira zabwino ngati anthu akuyenda mwachangu mphindi 20 tsiku lililonse. (Morita, E., et al., 2019)
Kuchita Zolimbitsa Thupi Kungathandize Kuchepetsa Kuopsa kwa Khansa ya Colon
Zochita zolimbitsa thupi zitha kukhala zoteteza kwambiri pakuchepetsa khansa ya m'matumbo. (National Cancer Institute. 2023) Ena amalingalira kuti kuchepetsa chiopsezo ndi 50%, ndipo kuchita masewera olimbitsa thupi kungathandizenso kupewa kubwereza pambuyo pa matenda a khansa ya m'matumbo, komanso 50% m'maphunziro ena kwa odwala omwe ali ndi khansa yamtundu wa II kapena III. (Schoenberg MH 2016)
Imfa idachepetsedwa ndi 23% mwa anthu omwe adachita masewera olimbitsa thupi kwa mphindi 20 kangapo pa sabata.
Odwala omwe ali ndi khansa ya m'matumbo osagwira ntchito omwe adayamba kuchita masewera olimbitsa thupi atazindikira kuti ali ndi zotulukapo zabwino kwambiri kuposa anthu omwe adangokhala chete, zomwe zikuwonetsa kuti sikunachedwe kuyamba kuchita masewera olimbitsa thupi.Schoenberg MH 2016)
Odwala omwe anali okhudzidwa kwambiri anali ndi zotsatira zabwino kwambiri.
Kupewa Kutsekula m'mimba kokhudzana ndi masewera olimbitsa thupi
Ena othamanga ndi oyenda amakumana ndi colon yothamanga kwambiri, zomwe zimayambitsa matenda otsegula m'mimba kapena zotayirira, zomwe zimadziwika kuti runner's trots. Mpaka 50% ya othamanga opirira amakumana ndi vuto la m'mimba panthawi yochita masewera olimbitsa thupi kwambiri. (de Oliveira, EP et al., 2014) Njira zopewera zomwe zingatsatidwe zikuphatikizapo.
Osadya mkati mwa maola awiri mukuchita masewera olimbitsa thupi.
Pewani kumwa mowa wa khofi ndi madzi otentha musanachite masewera olimbitsa thupi.
Ngati mumakhudzidwa ndi lactose, pewani mkaka kapena gwiritsani ntchito Lactase.
Imwani ma ounces 12-16 mphindi 5-15 zilizonse panthawi yolimbitsa thupi.
If kuchita masewera olimbitsa thupi kwa mphindi 90:
Imwani 12 - 16 fluid-ounce solution yokhala ndi 30-60 magalamu a chakudya, sodium, potaziyamu, ndi magnesium mphindi 5-15 zilizonse.
Thandizo la Aphunzitsi
Kudzimbidwa nthawi ndi nthawi kumatha ndi kusintha kwa moyo monga kuchuluka kwa fiber, masewera olimbitsa thupi, ndi madzi. Anthu omwe akukumana ndi ndowe zamagazi kapena hematochezia, posachedwapa ataya mapaundi 10 kapena kuposerapo, ali ndi kuchepa kwa magazi m'thupi, amayezetsa magazi obisika, kapena omwe ali ndi mbiri ya banja la khansa ya m'matumbo ayenera kuonana ndi dokotala kapena katswiri kuti achite zinazake. kuyezetsa matenda kuti muwonetsetse kuti palibe vuto lililonse kapena zovuta. (Jamshed, N. et al., 2011) Asanayambe kuyenda kukalandira chithandizo cha kudzimbidwa, anthu ayenera kuonana ndi achipatala kuti awone ngati kuli kotetezeka kwa iwo.
Ku Chiropractic Medical Chiropractic ndi Functional Medicine Clinic, madera athu omwe timachita nawo akuphatikizapo Wellness & Nutrition, Ululu Wosatha, Kuvulala Kwaumwini, Kusamalira Ngozi Yamagalimoto, Kuvulala Kwa Ntchito, Kupweteka Kwambiri, Kupweteka Kwambiri, Kupweteka kwa Pakhosi, Migraine Mutu, Kuvulala Kwa Masewera, Kwambiri. Sciatica, Scoliosis, Complex Herniated Discs, Fibromyalgia, Ululu Wosatha, Kuvulala Kwambiri, Kuwongolera Kupanikizika, Kuchiza Mankhwala Ogwira Ntchito, ndi ndondomeko za chisamaliro chapakati. Timayang'ana kwambiri zomwe zimakuthandizani kuti mukwaniritse zolinga zabwino ndikupanga gulu lotukuka kudzera munjira zofufuzira komanso mapulogalamu athanzi. Ngati chithandizo china chikufunika, anthu adzatumizidwa ku chipatala kapena dokotala woyenerera kuvulala, chikhalidwe, ndi / kapena matenda awo.
Kuyesa kwa Poop: Chiyani? Chifukwa chiyani? ndi Motani?
Zothandizira
Huang, R., Ho, SY, Lo, WS, & Lam, TH (2014). Zochita zolimbitsa thupi komanso kudzimbidwa kwa achinyamata aku Hong Kong. PloS imodzi, 9(2), e90193. doi.org/10.1371/journal.pone.0090193
Tantawy, SA, Kamel, DM, Abdelbasset, WK, & Elgohary, HM (2017). Zotsatira za zochitika zolimbitsa thupi zomwe zikufunsidwa komanso kuwongolera zakudya kuti athe kuthana ndi kudzimbidwa kwa amayi azaka zapakati onenepa kwambiri. Matenda a shuga, metabolic syndrome ndi kunenepa kwambiri: Zolinga ndi chithandizo, 10, 513-519. doi.org/10.2147/DMSO.S140250
Morita, E., Yokoyama, H., Imai, D., Takeda, R., Ota, A., Kawai, E., Hisada, T., Emoto, M., Suzuki, Y., & Okazaki, K. (2019). Maphunziro a Aerobic Exercise ndi Kuyenda Bwino Kumawonjezera Ma Bacteroides M'matumbo mwa Amayi Okalamba Athanzi. Zakudya, 11(4), 868. doi.org/10.3390/nu11040868
Schoenberg MH (2016). Zochita Zathupi ndi Zakudya Zakudya mu Pulayimale ndi Kupewa Kwambiri kwa Khansa ya Colourectal. Mankhwala a Visceral, 32 (3), 199-204. doi.org/10.1159/000446492
de Oliveira, EP, Burini, RC, & Jeukendrup, A. (2014). Madandaulo a m'mimba pakuchita masewera olimbitsa thupi: kuchuluka, etiology, ndi malingaliro azakudya. Mankhwala amasewera (Auckland, NZ), 44 Suppl 1 (Suppl 1), S79–S85. doi.org/10.1007/s40279-014-0153-2
Anthu omwe ali ndi vuto la m'mimba lomwe silingadziwike akhoza kukhala ndi vuto la m'mimba. Kodi kumvetsetsa mitunduyi kungathandize kupanga mapulani othandiza?
Matenda Ogwira Ntchito M'mimba
Kusagwira ntchito kwa m'mimba, kapena FGDs, ndi kusokonezeka kwa dongosolo la m'mimba momwe kupezeka kwa mapangidwe kapena minyewa sikungafotokozere zizindikiro. Matenda a m'mimba ogwira ntchito alibe zizindikiro zodziwika bwino ndipo amapezeka potengera zizindikiro. (Christopher J. Black, et al., 2020)
Zolinga za Roma
Ma FGDs adagwiritsa ntchito matenda odzipatula, kutanthauza kuti atha kupezeka pambuyo poti matenda odziwika bwino / odziwika adachotsedwa. Komabe, mu 1988, gulu la ochita kafukufuku ndi opereka chithandizo chamankhwala adakumana kuti akonze njira zolimba zodziwira mitundu yosiyanasiyana ya ma FGD. Njirayi imadziwika kuti Criteria ya Roma. (Max J. Schmulson, Douglas A. Drossman. 2017)
Kusanza ndi Aerophagia - cyclic vomiting syndrome, adolescent rumination syndrome, ndi aerophagia
Mavuto Okhudzana ndi Ululu Wam'mimba Ogwira Ntchito GI monga:
ntchito dyspepsia
IBS
Migraine ya m'mimba
Ubwana zinchito m`mimba ululu
Childhood zinchito m`mimba ululu syndrome
Kudzimbidwa - ntchito kudzimbidwa
Incontinence - kusakhazikika kwa chimbudzi
Matendawa
Ngakhale njira za ku Roma zimalola kuti matenda a FGD akhale ozikidwa pazizindikiro, wothandizira zaumoyo atha kuyesabe kuyesa koyezetsa kuti apewe matenda ena kapena kuyang'ana zovuta zamapangidwe zomwe zimabweretsa zizindikiro.
chithandizo
Ngakhale palibe zizindikiro zowoneka za matenda kapena zovuta zamapangidwe zomwe zingayambitse zizindikiro, sizikutanthauza kuti iwo chotheka ndi chotheka. Kwa anthu omwe akukayikira kuti ali ndi vuto la m'mimba kapena apezeka kuti ali ndi vuto logwira ntchito m'mimba, ndikofunikira kuti azigwira ntchito ndi wothandizira zaumoyo panjira yogwira ntchito. Njira zochiritsira zingaphatikizepo: (Asma Fikree, Peter Byrne. 2021)
Kuchiza thupi
Kusintha kwa zakudya ndi zakudya
Kusamalira maganizo
Psychotherapy
Mankhwala
Biofeedback
Kudya Bwino Kuti Mumve Bwino
Zothandizira
Black, CJ, Drossman, DA, Talley, NJ, Ruddy, J., & Ford, AC (2020). Kusagwira ntchito kwa m'mimba: kupita patsogolo pakumvetsetsa ndi kasamalidwe. Lancet (London, England), 396 (10263), 1664-1674. doi.org/10.1016/S0140-6736(20)32115-2
Schmulson, MJ, & Drossman, DA (2017). Zomwe Zatsopano ku Rome IV. Journal ya neurogastroenterology ndi motility, 23 (2), 151-163. doi.org/10.5056/jnm16214
Sperber, AD, Bangdiwala, SI, Drossman, DA, Ghoshal, UC, Simren, M., Tack, J., Whitehead, WE, Dumitrascu, DL, Fang, X., Fukudo, S., Kellow, J., Okeke , E., Quigley, EMM, Schmulson, M., Whorwell, P., Archampong, T., Adibi, P., Andresen, V., Benninga, MA, Bonaz, B., … Palsson, OS (2021). Kufalikira Padziko Lonse ndi Kulemedwa kwa Matenda Ogwira Ntchito M'mimba, Zotsatira za Rome Foundation Global Study. Gastroenterology, 160 (1), 99-114.e3. doi.org/10.1053/j.gastro.2020.04.014
Hyams, JS, Di Lorenzo, C., Saps, M., Shulman, RJ, Staiano, A., & van Tilburg, M. (2016). Mavuto Ogwira Ntchito: Ana ndi Achinyamata. Gastroenterology, S0016-5085(16)00181-5. Pitani patsogolo pa intaneti. doi.org/10.1053/j.gastro.2016.02.015
Fikree, A., & Byrne, P. (2021). Kuwongolera magwiridwe antchito am'mimba. Mankhwala achipatala (London, England), 21 (1), 44-52. doi.org/10.7861/clinmed.2020-0980
Zizindikiro monga kupweteka kwa m'mimba, kutupa, ndi matumbo ovuta ndizofala. Zakudya ndi madzi abwino amadzimadzi ali ndi gawo lalikulu pa thanzi la m'mimba, makamaka pochepetsa komanso kupewa kudzimbidwa. Zakudya zokhala ndi fiber yambiri, prebiotics, ndi madzi okwanira okwanira kuchokera ku zakudya ndi zakumwa ndizofunika kuti matumbo asamayende bwino.
Fiber amapezeka mumbewu zonse, zowuma, zipatso, ndi ndiwo zamasamba.
Ulusi wosungunuka ndi wosasungunuka ndi wofunikira m'mimba.
Kukhazikika pakuphatikiza zipatso zokhala ndi ulusi wambiri, masamba, ndi mbewu zonse.
Zakudya zokhala ndi ma prebiotics monga zakudya zofufumitsa zimalimbikitsidwa mukadzimbidwa.
The analimbikitsa zakudya kudzimbidwa, malinga ndi dietitian zikuphatikizapo.
mapeyala
Mapeyala amatha kuphatikizidwa ndi chilichonse ndipo amakhala ndi michere yambiri komanso fiber.
Peyala imodzi imakhala ndi pafupifupi 13.5 magalamu a fiber.
Peyala imodzi ipereka pafupifupi theka la tsiku ndi tsiku.
Zipatso zina za ulusi wambiri: makangaza, magwava, raspberries, mabulosi akuda, ndi passionfruit.
Gwiritsani ntchito kefir kapena yoghurt ngati maziko ndikuwongolera ndi zipatso zokhala ndi fiber monga mango, blueberries, ndi kiwi.
zokhwasula-khwasula
Sakanizani zokhwasula-khwasula ndi mbale ya fiber ndi prebiotics.
Mtedza, tchizi, crackers, zipatso, ndi yogati kapena diphu ya avocado.
oatmeal
Yesani oat bran kuti muwonjezere fiber.
Kuwaza gawo la mbewu za flaxseed, mbewu za chia, kapena mbewu hemp kwa fiber yowonjezera komanso mafuta abwino.
wangwiro
Zakudya za yogurt akhoza kuonjezera zakudya, kukoma, ndi maonekedwe mu mbale.
Ikani pa yoghurt yomwe mumakonda ndi granola, mtedza, zipatso, ndi mbewu.
Msuzi wa Grain Bowl
Ulusi wopezeka mumbewu zonse monga balere, farro, ndi quinoa, umathandizira kulimbikitsa chimbudzi.
Pangani mbale ndi a maziko a tirigu, kenako pamwamba ndi mapuloteni, masamba atsopano kapena okazinga, mapeyala, ndi kuvala.
Lankhulani ndi katswiri wodziwa za kadyedwe kake kapena wopereka chithandizo chamankhwala kuti mukambirane njira zoyenera kudya.
Kulinganiza Thupi ndi Metabolism
Zothandizira
Arce, Daisy A et al. "Kuwunika kwa kudzimbidwa." Dokotala waku America vol. 65,11 (2002): 2283-90.
Bharucha, Adil E. "Constipation." Kuchita bwino kwambiri & kafukufuku. Clinical gastroenterology vol. 21,4 (2007): 709-31. doi:10.1016/j.bpg.2007.07.001
Gray, James R. “Kodi kudzimbidwa kosatha ndi chiyani? Tanthauzo ndi matenda. " Canadian Journal of Gastroenterology = Journal Canadien de Gastroenterology vol. 25 Suppl B, Suppl B (2011): 7B-10B.
Jani, Bhairvi, ndi Elizabeth Marsikano. "Kudzimbidwa: Kuwunika ndi Kuwongolera." Mankhwala a Missouri vol. 115,3 (2018): 236-240.
Naseer, Maliha, et al. "Zotsatira Zochizira za Prebiotics pa Kudzimbidwa: Kuwunika Kwadongosolo." Panopa chipatala pharmacology vol. 15,3, 2020 (207): 215-10.2174. doi:1574884715666200212125035/XNUMX
National Institute of Diabetes and Digestive and Kidney Diseases. Zizindikiro ndi Zomwe Zimayambitsa Kudzimbidwa.
National Institute of Diabetes and Digestive and Kidney Disease. Digestive Dongosolo Lanu ndi Momwe Imagwirira Ntchito.
Sinclair, Marybetts. "Kugwiritsa ntchito kutikita minofu m'mimba pochiza kudzimbidwa kosatha." Journal of bodywork and movement Therapies vol. 15,4 (2011): 436-45. doi:10.1016/j.jbmt.2010.07.007
Dr. Jimenez, DC, akuwonetsa momwe kugwirizana kosalekeza kwa kagayidwe kachakudya monga kutupa ndi kukana insulini kumapangitsa kuti thupi likhale logwirizana mumagulu a 2. Zinthu zambiri nthawi zambiri zimakhudza thanzi lathu komanso thanzi lathu. M'chiwonetsero chamasiku ano, tipitiliza momwe matenda osachiritsika a metabolic amakhudzira ziwalo zofunika kwambiri ndi ziwalo. Zitha kupangitsa kuti pakhale zoopsa zomwe zimagwirizanitsidwa ndi zizindikiro zowawa m'minofu, mafupa, ndi ziwalo zofunika. Part 1 adawunikanso momwe kuchuluka kwa ziwopsezo monga kukana insulini ndi kutupa kumakhudzira thupi ndikupangitsa kuti minofu ndi mafupa azimva kupweteka. Timatchula odwala athu kwa madokotala ovomerezeka omwe amapereka chithandizo chamankhwala kwa anthu omwe akudwala matenda osachiritsika okhudzana ndi kulumikizidwa kwa metabolic. Timalimbikitsa wodwala aliyense ngati kuli koyenera powatumiza kwa azachipatala omwe amagwirizana nawo malinga ndi zomwe akudziwa kapena zomwe akufuna. Timamvetsetsa ndikuvomereza kuti maphunziro ndi njira yabwino kwambiri pofunsa mafunso ofunikira kwa odwala athu powapempha ndi kuvomereza. Dr. Alex Jimenez, DC, amagwiritsa ntchito chidziwitsochi ngati ntchito yophunzitsa. chandalama
Momwe Chiwindi Chimayenderana ndi Matenda a Metabolic
Chifukwa chake titha kuyang'ana kuchiwindi kuti tipeze zizindikiro zoyambirira za chiopsezo cha mtima. Kodi tingachite bwanji zimenezi? Chabwino, tiyeni timvetsetse biochemistry ya chiwindi. Chifukwa chake mu cell hepatocyte yathanzi ya chiwindi, mukamachulukitsa insulin yotulutsidwa chifukwa panali chakudya chomwe chimafunikira kuti glucose amwe, zomwe mumayembekezera ngati cholandilira cha insulin chikugwira ntchito ndikuti glucose amalowa. inasanduka mphamvu. Koma vuto ndi ili. Pamene hepatocyte ili ndi insulin zolandilira zomwe sizigwira ntchito, mumakhala ndi insulin kunja, ndipo shuga sanalowemo. lowetsani mkati. Kotero chimene icho chimachita ndikuzimitsa mafuta a asidi oxidation, kuganiza, “Anyamata, sitifunika kuwotcha zidulo zathu zamafuta. Tili ndi glucose akubwera. "
Chifukwa chake ngati glucose kulibe, ndipo simukuwotcha mafuta acids, ndizofala kwambiri kuti anthu azitopa chifukwa palibe chomwe chikuyaka mphamvu. Koma apa pali sequela yachiwiri; mafuta acid onsewo akupita kuti, chabwino? Chabwino, chiwindi chikhoza kuyesa kuwayikanso ngati ma triglycerides. Nthawi zina, amakhala mu hepatocyte kapena amachotsedwa m'chiwindi kupita m'magazi monga VLDL kapena lipoprotein yotsika kwambiri. Mutha kuziwona ngati kusintha kwakukulu kwa triglyceride mu gulu lokhazikika la lipid. Kotero, pamene tonse tikukamba za kupeza mulingo wa triglyceride mpaka 70 monga cholinga chanu cha 8+, ndikayamba kuwona ma triglycerides akukwera, timadikirira mpaka atafika 150, ngakhale ndiko kudulidwa kwa ma lab athu. Tikawona pa 150, timadziwa kuti akuthamangitsa triglycerides m'chiwindi.
Chifukwa chake izi zimachitika nthawi zambiri tisanapeze kusala kudya kwa glucose. Chifukwa chake yang'anani ma triglycerides anu, ma triglycerides osala kudya, ngati chizindikiro chodziwika bwino cha kusagwira ntchito kwa insulin. Kotero ichi ndi chithunzi china chomwe chimati ngati triglycerides ikupangidwa chifukwa mafuta acids akukhala oxidized, akhoza kukhala m'chiwindi. Ndiye izo zimapangitsa steatosis kapena chiwindi chamafuta, kapena amatha kukankhidwira kunja, ndipo amasandulika kukhala ma lipoprotein. Tikambirana izi mumphindi chabe. Thupi liri ngati, "Titani ndi mafuta acids awa?" Sitingayese kuwakankhira m’malo chifukwa palibe amene amawafuna. Kufikira pamenepo, chiŵindi chili ngati, “Sindikuzifuna, koma ndikhala nazo zina.” Kapena chiŵindi chikananyamula mafuta a asidi ameneŵa n’kumamatira m’mitsempha ya magazi.
Ndiyeno mitsempha ya magazi ndi mitsempha zimakhala monga, “Chabwino, ine sindikuzifuna izo; Ndiziyika pansi pa endothelium yanga. Ndipo ndimomwe mungapangire atherogenesis. Minofu imakhala ngati, "Sindikufuna, koma nditenga." Umu ndi momwe mumapezera mikwingwirima yamafuta muminofu yanu. Chifukwa chake, chiwindi chikawotchedwa ndi steatosis, kutupa kumachitika m'thupi ndipo kumapangitsa kuti chakudya chiziyenda mkati mwa hepatocyte, ndikuwononga chiwindi. Inu mukupeza imfa ya ma cell; mukupeza fibrosis, zomwe zimangowonjezera zomwe zimachitika tikapanda kuthana ndi zovuta zazikulu za chiwindi chamafuta: kutupa ndi kukana insulini. Chifukwa chake, timayang'ana zowoneka bwino za AST, ALT, ndi GGT; kumbukirani kuti ndi enzyme yochokera ku chiwindi.
Ma Hormone Enzymes & Kutupa
Ma enzymes a GGT m'chiwindi ndi ozindikira utsi ndipo amatiuza kuchuluka kwa kupsinjika kwa okosijeni komwe kumachitika. Kodi tidzayang'ana pa HSCRP ndi APOB kuti tiwone zotsatira za chiwindi ichi? Kodi ikuyamba kutaya mafuta ochulukirapo kudzera mu VLDL, APOB, kapena triglycerides? Ndipo momwe amasankhira kuti ndi chibadwa chabe, moona mtima. Chifukwa chake ndimayang'ana zolembera m'chiwindi kuti zindiuze zomwe zikuchitika m'chiwindi monga chizindikiro cha zomwe zikuchitika kulikonse. Chifukwa chimenecho chikhoza kukhala malo ofooka amtundu wa munthu, anthu ena amakhala pachiwopsezo cha majini malinga ndi mbiri yawo ya lipid. Kufikira pamenepo, titha kuyang'ana china chake chotchedwa metabolic dyslipidemia. Mukudziwa izi ngati ma triglycerides okwera komanso otsika HDL. Mukhoza kuyang'ana makamaka chiŵerengero; mulingo woyenera ndi atatu ndi kutsika. Imayamba kuchokera pa atatu mpaka asanu kenako asanu mpaka eyiti, ngati eyiti ndi pafupifupi pathognomonic ya insulin kukana. Mukungofikira kukhala osamva insulin.
Pamene chiwerengero chikuchulukirachulukira pa chiŵerengero cha HDL, imeneyo ndi njira yosavuta, yosavuta yowonera kukana kwa insulini. Tsopano anthu ena amayang'ana 3.0 pa izi koma amakhalabe ndi insulin kukana. Ndiye pali mayeso ena omwe mumachita. Iyi ndi njira yopezera omwe amawonetsa kukana kwa insulini kudzera mu lipids. Ndipo kumbukirani, aliyense ndi wosiyana. Azimayi omwe ali ndi PCOS amatha kukhala ndi lipids odabwitsa koma amatha kusonyeza kuwonjezeka kapena kuchepa kwa mahomoni okhudzana ndi insulini, estrogen, ndi kutupa. Chifukwa chake yang'anani china chake osati mayeso amodzi kapena chiŵerengero kuti muwonetse ngati ali nacho. Mukuyang'ana kuti muwone komwe kungakhale komwe tingapezeko chidziwitso.
Choncho tiyeni tigwiritse ntchito mawu abwino. Munthu wathanzi ali ndi VLDL yomwe imawoneka ngati yathanzi labwino kukula m'matupi ake, ndipo amakhala ndi LDL ndi HDL yokhazikika. Koma tsopano onani zomwe zimachitika mukapeza insulin kukana. Ma VLDL awa amayamba kupopa ndi triglycerides. N’chifukwa chake akunenepa. Ndi lipotoxicity. Chifukwa chake ngati mutayamba kuyang'ana manambala atatu a VLDL mu mbiri ya lipoprotein, mudzawona kuti nambalayo ikukwera, ndipo pali zambiri, ndipo kukula kwake ndikwambiri. Tsopano ndi LDL, chomwe chimachitika ndikuti kuchuluka kwa cholesterol mkati mwa pamwamba ndi pansi ndi chimodzimodzi. Ngati nditulutsa mabaluni amadzi onsewa, ndi kuchuluka komweko kwa cholesterol ya LDL. Komabe, kuchuluka kwa cholesterol ya LDL mu insulin kukana kumapakidwanso mu LDL yaying'ono.
Kodi Functional Medicine Imagwira Ntchito Motani?
Tsopano tamva kuti pakhoza kukhala ena mwa inu omwe sangathe kapena alibe mwayi woyezetsa izi, kapena odwala anu sangakwanitse, ndichifukwa chake tidayankha mafunsowo ndikuyang'ana zidziwitso zina za kukana insulini ndikuchiza chomwe chimayambitsa kukhudza thupi. Yang'anani zizindikiro za kutupa ndi mbiri zina zophatikizika za kukana insulini. Nambala ya tinthu tating'onoting'ono imakhala yokwera kwambiri pamene akukana insulini. Chifukwa chake cholesterol ndi yofanana, pomwe tinthu tating'onoting'ono timakwera kwambiri, ndipo LDL yaying'ono imakhala ya atherogenic. Chitani chifukwa kaya muli ndi mwayi wodziwa kapena ayi, payenera kukhala chinachake m'mutu mwanu chomwe chimati, "Munthu, ngakhale cholesterol ya LDL ya munthu uyu ikuwoneka bwino, ali ndi matani otupa ndi kukana insulini; Sindikutsimikiza kuti alibe nambala yokulirapo. ” Mungaganize kuti amachita zimenezi kuti atetezeke.
Chinanso chomwe chimachitika pakukana kwa insulin ndikuti HDL kapena cholesterol yathanzi imakhala yaying'ono. Chifukwa chake sizabwino kwambiri chifukwa mphamvu ya efflux ya HDL imachepetsedwa ikakhala yaying'ono. Chifukwa chake timakonda HDL yayikulu, ngati mungafune. Kupeza mayesowa kungakupatseni chidziwitso chotsimikizika cha zomwe zikuchitika ndi wodwala wanu kuchokera ku cardiometabolic.
Zikafika pamayesowa, ndikofunikira kuwagwiritsa ntchito kudziwa nthawi yomwe wodwalayo ali ndi kutupa kapena kukana insulini m'matupi awo, zomwe zimakhudza moyo wawo. Komabe, anthu ambiri nthawi zambiri amawonetsa kuti mayesowa ndi okwera mtengo ndipo amapita ndi muyezo wa golide woyezetsa kuti angakwanitse kugula ndikutha kusankha ngati kuli koyenera kuti akhale ndi thanzi labwino komanso thanzi lawo.
Yang'anani Njira Zowopsa za Cardiometabolic
Chifukwa chake zikafika pamachitidwe owopsa a cardiometabolic factor, timayang'ana mbali ya insulin ndi momwe imalumikizirana ndi kusagwira bwino ntchito kwa mitochondrial komwe kumakhudzana ndi kukana insulini komanso kutupa. Nkhani yofufuza imanena za momwe zovuta ziwiri za mitochondrial zingakhudzire thupi. Chabwino, tiyeni tikambirane nkhani yoyamba, yomwe ndi nkhani ya kuchuluka. Mmodzi akhoza kukhala endotoxins omwe timakumana nawo m'malo athu, kapena awiri; ukhoza kufalitsidwa kuchokera ku mibadwomibadwo kupita ku mibadwo. Chifukwa chake mitundu iwiriyi imatha kuwonetsa kuti mulibe mitochondria yokwanira. Ndiye kuti ndi nkhani ya kuchuluka. Vuto lina ndilabwino. Inu muli nazo zochuluka za izo; sagwira ntchito bwino, kotero alibe kutulutsa kwakukulu kapena zotsatira zabwinobwino. Tsopano izi zimasewera bwanji mthupi? Kotero kunja kwa m'mphepete, minofu yanu, adipocyte, ndi chiwindi, muli ndi mitochondria m'maselo amenewo, ndipo ndi ntchito yawo kulimbikitsa loko ndi kugwedezeka. Chifukwa chake ngati mitochondria yanu ili m'chiwerengero choyenera, muli ndi zambiri zoti mulimbikitse loko ya insulin komanso kunjenjemera.
Zosangalatsa, chabwino? Kotero apa ndichidule, ngati mulibe mitochondria yokwanira, yomwe ili vuto m'mphepete mwake, mumapeza insulini kukana chifukwa loko ndi jiggle sizikuyenda bwino. Koma ngati mulibe mitochondria yomwe ikugwira ntchito bwino mu kapamba, makamaka mu cell ya beta, simumatulutsa insulini. Chifukwa chake mumapezabe hyperglycemia; mulibe insulin yambiri. Izi zikachitika, timadziwa kuti ubongo wanu uyenera kukhala ukupweteka, koma mwachiyembekezo, udzagwirizana pang'onopang'ono.
Nkhani ina imanenanso kuti imagwirizanitsa kusagwira ntchito kwa mitochondrial ndi matenda a shuga amtundu wachiwiri, ndipo zakudya zopanda thanzi za amayi zimatha kuyambitsa. Uyu amalankhula za momwe chiwindi chamafuta chimalumikizidwa ndi lipotoxicity, sichoncho? Ndiko kuchuluka kwa mafuta acid, ndi kupsinjika kwa okosijeni, zomwe, kumbukirani, ndizochokera ku kutupa. Kuchepa kwa ATP ndi kukanika kwa mitochondrial. Izi zikachitika, zimatha kukhudza chiwindi, chomwe chimasandulika kukhala chiwindi chamafuta, ndipo chimathanso kulumikizidwa ndi vuto la m'matumbo, lomwe limayambitsa kutupa kosatha, kukwera kwa insulin kukana, kulephera kwa mitochondrial, ndi zina zambiri. Matenda a kagayidwe kachakudyawa amalumikizidwa, ndipo pali njira zochepetsera zizindikirozi kuti zisakhudze thupi.
Kutsiliza
Akamacheza ndi madokotala awo, odwala ambiri amadziwa kuti madalaivala omwewo amakhudzanso mitundu ina yambiri ya phenotype, yomwe nthawi zambiri imachokera ku kutupa, insulini, ndi kawopsedwe. Chifukwa chake anthu ambiri akazindikira kuti izi ndizomwe zimayambitsa, madotolo azigwira ntchito ndi othandizira azachipatala ambiri kuti apange njira zochiritsira zomwe zimagwira ntchito payekha. Chifukwa chake kumbukirani, nthawi zonse muyenera kugwiritsa ntchito mzere wanthawi ndi masanjidwewo kuti muthandizire kudziwa komwe mumayambira ndi wodwala uyu, ndipo kwa anthu ena, zitha kukhala kuti mungosintha pang'ono moyo wanu chifukwa zonse zomwe iwo amachita. Iwo akugwira ntchito ndikusintha kuchuluka kwa thupi lawo. Chifukwa chake ndi limodzi mwamadalitso amankhwala ogwira ntchito omwe tidatha kuzimitsa kutupa m'matumbo, zomwe zimathandiza kuchepetsa chiwopsezo cholemetsa chiwindi. Zimathandizanso kuti munthuyo adziwe zomwe zimagwira ntchito kapena zomwe sizikugwira ntchito ndi matupi awo ndikutenga njira zing'onozing'onozi kuti akhale ndi thanzi labwino.
Tikukhulupirira kuti muli ndi maso atsopano okhudza kutupa, insulini, ndi kawopsedwe komanso momwe zimakhalira pamizu yazinthu zambiri zomwe odwala anu akukumana nazo. Ndipo momwe kudzera m'moyo wosavuta komanso wogwira mtima komanso njira zopezera zakudya, mutha kusintha ma signature ndikusintha mawonekedwe awo lero ndi zoopsa zomwe ali nazo mawa.
Dr. Alex Jimenez, DC, akuwonetsa momwe kugwirizana kwa kagayidwe ka metabolic kumapangitsa kuti pakhale matenda aakulu aakulu mumagulu a 2. Zinthu zambiri nthawi zambiri zimakhudza thanzi lathu komanso thanzi lathu. Zitha kupangitsa kuti pakhale zoopsa zomwe zimagwirizanitsidwa ndi zizindikiro zowawa m'minofu, mafupa, ndi ziwalo zofunika. Gawo 2 lipitiliza kufotokozera za kulumikizana kwa metabolic ndi matenda akulu akulu. Timatchula odwala athu kwa madokotala ovomerezeka omwe amapereka chithandizo chamankhwala kwa anthu omwe akudwala matenda osachiritsika okhudzana ndi kulumikizidwa kwa metabolic. Timalimbikitsa wodwala aliyense ngati kuli koyenera powatumiza kwa azachipatala omwe amagwirizana nawo malinga ndi zomwe akudziwa kapena zomwe akufuna. Timamvetsetsa ndikuvomereza kuti maphunziro ndi njira yabwino kwambiri pofunsa mafunso ofunikira kwa odwala athu powapempha ndi kuvomereza. Dr. Jimenez, DC, amagwiritsa ntchito chidziwitsochi ngati ntchito yophunzitsa. chandalama
Momwe Kutupa Kumakhudzira Thupi
Dr. Alex Jimenez, DC, akupereka: Kotero apa muli ndi ma adipocyte owonda kumanzere, ndiyeno pamene ayamba kuchulukirachulukira ndi kulemera kwa ma cell, mutha kuwona macrophage awo, nthiti zobiriwira zikubwera mozungulira, zikunena, “Hey, chikuchitika ndi chiyani kuno? Sizikuwoneka bwino.” Chifukwa chake akufufuza, ndipo izi zimayambitsa kufa kwa maselo amderalo; ndi gawo chabe la zotupa zotupa. Kotero palinso njira ina yomwe ikuchitika apa. Ma adipocyte amenewo samangochulukira mwangozi; nthawi zambiri zimagwirizana ndi calorie surfette. Chifukwa chake kuchuluka kwa michere iyi kumawononga endoplasmic reticulum, zomwe zimapangitsa kutupa kwambiri. Zomwe maselowa ndi adipocytes akuyesera kuchita ndikudziteteza ku glucose ndi lipo toxicity.
Ndipo selo lonse, selo la adipocyte, likupanga makapu awa omwe akuyesa kunena kuti, “Chonde, siyani, sitingatengenso shuga, sitingathe kutenganso lipids. Ndi njira yodzitetezera yomwe imadziwika kuti insulin kukana. Sichinthu china chongochitika mwachisawawa. Ndi njira ya thupi yoyesera kuteteza shuga ndi lipotoxicity. Tsopano kuti alamu ya kutupa ikuchitika mochuluka kuposa ma adipocytes, ikukhala mwadongosolo. Minofu ina ndi ziwalo zikuyamba kumva zolemetsa zomwezo za calorie surfette, zomwe zimayambitsa kutupa ndi kufa kwa cell. Chifukwa chake shuga ndi lipotoxicity zimawoneka ngati chiwindi chamafuta mukamagwira ntchito ndi chiwindi. Ndipo mutha kukhala nazo monga momwe chiwindi chamafuta chimapitira ku cirrhosis ndi kufa kwa hepatocyte. Zomwezo zimagwirira ntchito zomwe zikuchitika m'maselo a minofu. Chifukwa chake ma cell athu amthupi amawona kufa kwa cell pambuyo potupa ndikuwona kuyika kwamafuta.
Njira yabwino yoganizira izi ndi, mwachitsanzo, ng'ombe zomwe zimadyetsedwa kuti zidye komanso momwe zimapangidwira. Ndiye kusungirako mafuta. Ndipo mwa anthu, mutha kuganiza za momwe anthu amakhalira sarcopenic pomwe akuchulukirachulukira kukana insulin. Ndichimodzimodzinso pamene minofu ya thupi ikuyesera kudziteteza ku glucolipotoxicity, zomwe zimayambitsa kutupa komweko. Imakhala kuyankha kwa endocrine ikayamba kulunjika minofu ina yozungulira, kaya chiwindi, minofu, fupa, kapena ubongo; ndi chirichonse chimene chikuchitika; iwo ali mu visceral adipocytes omwe amatha kuchitika mu minofu ina. Ndiye ndiye zotsatira zanu za paracrine. Ndiyeno icho chikhoza kukhala cha virus, ngati inu mungathe.
Kutupa Kumakhudzana ndi Kukaniza kwa insulin
Dr. Alex Jimenez, DC, akupereka: Mukupeza kuyankha kwapagulu komanso mwadongosolo kothandizira kutupa kophatikizana ndi insulin kukana, ndikubwerera ku njira yodzitetezera ku glucose ndi lipotoxicity. Apa mukuwona momwe mitsempha yamagazi yomwe ili m'mitsempha yathu imagwidwa ndi kuyika kwamafuta ndi kufa kwa maselo. Chifukwa chake mudzawona mitsempha yamagazi yotayirira ndi ma depositi amafuta, ndipo mudzawona kuwonongeka ndi pro-atherogenesis. Tsopano, izi ndi zomwe tidafotokozera mu AFMCP pagawo la cardiometabolic. Ndipo ndiye physiology kumbuyo kwa insulin receptor. Izi zimatchedwa lock and jiggle technique. Chifukwa chake muyenera kukhala ndi zotsekera insulin mu cholandilira insulin pamwamba., chomwe chimadziwika kuti loko.
Kenako pamakhala phosphorylation cascade yotchedwa jiggle yomwe imapangitsa kuti mayendedwe a glucose-4 atsegule ma gluco-4 receptors kuti alowe mu cell kuti akhale glucose, omwe amagwiritsidwa ntchito ngati mphamvu. kupangidwa ndi mitochondria. Zachidziwikire, kukana kwa insulin ndi komwe cholandiriracho sichimamamatira kapena kulabadira. Ndipo kotero sikuti mumangolephera kulowetsa shuga m'maselo kuti mupange mphamvu, komanso mukupereka mawonekedwe a hyper insulin m'mphepete mwake. Chifukwa chake mumapeza hyperinsulinemia komanso hyperglycemia mumakina awa. Ndiye titani pamenepa? Chabwino, zakudya zambiri zawonetsedwa kuti zithandizire kutseka ndi kusuntha zinthu zomwe zingapangitse onyamula glucose-4 akubwera mozungulira.
Mankhwala Oletsa Kutupa Amachepetsa Kutupa
Dr. Alex Jimenez, DC, akupereka: Mukuwona izi zomwe zalembedwa apa: vanadium, chromium, sinamoni alpha lipoic acid, biotin, ndi wosewera wina watsopano, berberine. Berberine ndi botanical yomwe imatha kuchepetsa zizindikiro zonse zoyambira zotupa. Chifukwa chake zomwe zimatsogolera ma comorbidities nthawi zambiri ndikusokonekera kwa insulin. Chabwino, ndi chiyani chomwe chimatsogolera kukanika kwa insulin nthawi zambiri? Kutupa kapena kawopsedwe. Chifukwa chake ngati berberine ikuthandizira vuto loyambitsa kutupa, ithana ndi kutsika kwa insulin kukana ndi zovuta zonse zomwe zingachitike. Chifukwa chake ganizirani berberine ngati njira yanu. Chifukwa chake, izi zikuwonetsani kuti ngati mutha kuchepetsa kutupa pamwamba apa, mutha kuchepetsa zotsatira zambiri kutsika. Berberine makamaka ikuwoneka kuti ikuchita mu wosanjikiza wa microbiome. Imawongolera matumbo a microbiota. Zitha kupanga kulolerana kwa chitetezo chamthupi, chifukwa chake osapereka kutupa kwambiri.
Chifukwa chake ganizirani berberine ngati chida chimodzi chomwe mungagwiritse ntchito kuthandizira kulephera kwa insulini komanso zovuta zokhudzana ndi insulin kukana. Berberine akuwoneka kuti akuwonjezera kutulutsa kwa insulin receptor, kotero loko ndi jiggle zimagwira ntchito bwino ndikuwongolera kutsika ndi zonyamula glucose-4. Ndilo njira imodzi yomwe mungayambire kupeza chomwe chimayambitsa zinthu zambiri zomwe takambirana mukawona paracrine ndi endocrine glucose kawopsedwe, kuwonongeka kwa chiwalo cha lipotoxicity. Tsopano njira ina yoti muganizire ndikugwiritsa ntchito NF kappa B. Chifukwa chake cholinga ndikusunga NF kappa B kuti ikhale yokhazikika chifukwa bola ngati sakusuntha, zizindikiro zambiri zotupa siziyamba.
Ndiye cholinga chathu ndikusunga NF kappa B kuti ikhale yokhazikika. Kodi tingachite bwanji zimenezi? Chabwino, titha kugwiritsa ntchito NF kappa B inhibitors. Chifukwa chake mukuwonetsa njira zochizira matenda aliwonse okhudzana ndi kukanika kwa insulin, pali njira zambiri zochepetsera izi zomwe zimakhudza matupi athu. Chifukwa chake mutha kukhudza mwachindunji kukana kwa insulini pogwiritsa ntchito mankhwala oletsa kutupa kapena kuthandizira mosadukiza insulin kukana kapena kusagwira ntchito kwa insulin pothandizira zinthu zolimbana ndi kutupa. Chifukwa ngati mukukumbukira, kukanika kwa insulin ndizomwe zimayambitsa zovuta zonsezo. Koma chomwe chimayambitsa kusagwira ntchito kwa insulin nthawi zambiri ndi kutupa kapena poizoni. Chifukwa chake cholinga chathu ndikuthana ndi zinthu zomwe zimalimbikitsa kutupa. Chifukwa ngati titha kuthana ndi zinthu zoyambitsa kutupa ndikuchotsa kusagwira bwino kwa insulin mumphukira, titha kupewa kuwonongeka kwa chiwalo chonse kapena kuwonongeka kwa chiwalo.
Kuchepetsa Kutupa M'thupi
Dr. Alex Jimenez, DC, akupereka: Tiyeni tipitirire ku gawo lotsatira lomwe mutha kukulitsa kapena kuchepetsa kutupa ndi kuwonongeka kwa supu ya insulin ngati mungafune, kuti majini asambe m'thupi. Izi ndizomwe mumamva nthawi zambiri muzofotokozera zathu, ndipo ndichifukwa choti, muzamankhwala ogwira ntchito, timathandizira kukonza matumbo. Nthawi zambiri ndi kumene muyenera kupita. Ndipo iyi ndiye pathophysiology chifukwa chake timachita izi muzamankhwala a cardiometabolic. Chifukwa chake ngati muli ndi zakudya zopanda pake kapena zachisoni, zakudya zamakono zakumadzulo zomwe zili ndi mafuta oyipa, zitha kuwononga mwachindunji ma microbiome anu. Kusintha kumeneku kwa microbiome kumatha kupangitsa kuti matumbo achuluke. Ndipo tsopano lipopolysaccharides amatha kusuntha kapena kutayikira m'magazi. Kufikira pamenepo, chitetezo cha mthupi chimati, “Ayi, bwanawe. Simukuyenera kukhala muno.” Muli ndi ma endotoxins mmenemo, ndipo tsopano pali kuyankha kwapang'onopang'ono komanso mwadongosolo kuti kutupa kumayendetsa kusokonekera kwa insulin, komwe kumayambitsa zovuta za metabolic zomwe zimabwera pambuyo pake.
Chilichonse chomwe munthu amakhala nacho mwachibadwa, chimasindikizidwa pa epigenetically. Chifukwa chake kumbukirani, ngati mutha kuthana ndi kutupa kwa microbiome, kutanthauza kuti pangani ma microbiome olekerera komanso olimba, mutha kuchepetsa kamvekedwe ka kutupa kwa thupi lonse. Ndipo mukachepetsa izi, zikuwonetsedwa kuti zimayika chidwi cha insulin. Chifukwa chake kutsika kwa kutupa, kumapangitsanso chidwi cha insulin chokhudzana ndi ma microbiome. Modabwitsa, zawonetsedwa kuti ma probiotics amalumikizidwa ndi kuwongolera kwa insulin. Chifukwa chake ma probiotics oyenera adzapanga kulolerana kwa chitetezo chamthupi. Mphamvu ya Microbiome ndi kusinthasintha kumachitika ndi ma probiotics. Chifukwa chake chidwi cha insulin chimasungidwa kapena kubwezeredwa kutengera komwe muli. Chifukwa chake chonde lingalirani izi ngati njira ina yosalunjika kapena njira yochizira yomwe imathandizira thanzi la cardiometabolic kwa odwala.
Probiotics
Dr. Alex Jimenez, DC, akupereka: Chifukwa chake pankhani ya ma probiotics, tidzawagwiritsa ntchito mwa munthu yemwe nthawi yomweyo atha kukhala ndi matenda am'mimba kapena osadya chakudya. Titha kusankha ma probiotics pa NF kappa B inhibitors ngati alinso ndi zovuta za insulin. Koma ngati ali ndi mavuto ambiri okhudza ubongo, tikhoza kuyamba ndi NF kappa B. Choncho, ndi momwe mungasankhire zomwe mungasankhe. Tsopano, kumbukirani, polankhula ndi odwala, ndikofunikira kukambirana momwe kadyedwe kawo kamayambitsa kutupa m'matupi awo. M'pofunikanso kuzindikira kuti si khalidwe kukambirana; ndi kuchuluka kukambirana ndi chitetezo kukambirana.
Ndipo monga mukukumbukira, tidalankhula dzulo kuti insulin yosala m'munsi mwa gawo loyamba la magawo anu a insulin yosala kudya ikhoza kukhala komwe mukufuna kupita. Ndipo kwa ife ku US, izi zimakhala pakati pa zisanu ndi zisanu ndi ziwiri ngati unit. Chifukwa chake zindikirani kuti iyi ndiye pathophysiology yamtundu wachiwiri wa shuga. Chifukwa chake mtundu wachiwiri wa shuga ukhoza kuchitika chifukwa chokana insulini; Zitha kuchitikanso chifukwa cha zovuta za mitochondrial. Chifukwa chake pathophysiology yamtundu wachiwiri wa matenda a shuga atha kukhala chifukwa kapamba anu satulutsa insulin yokwanira. Ndiye kachiwiri, awa ndi ochepa 20% omwe timakamba za anthu ambiri omwe akudwala matenda a shuga amtundu wachiwiri; ndi chifukwa chokana insulini, monga momwe tingaganizire, kuchokera ku vuto la hyperinsulinemia. Koma pali gulu ili la anthu omwe awononga mitochondria, ndipo samatulutsa insulini.
Chifukwa chake shuga wawo wam'magazi amakwera, ndipo amadwala matenda a shuga amtundu wachiwiri. Chabwino, ndiye funso ndilakuti, ngati pali vuto ndi ma cell a pancreatic beta, chifukwa chiyani pali vuto? Kodi shuga akukwera chifukwa minofu imakhala ndi insulin kukana, kotero siyimatha kugwira ndikubweretsa glucose? Ndiye kodi ndi chiwindi chomwe chimalimbana ndi insulini m'chiwindi chomwe sichingatenge glucose kuti chikhale ndi mphamvu? Chifukwa chiyani glucose uyu akuyendayenda m'magazi? Ndi zomwe uku ndikutanthauzira. Chifukwa chake gawo lothandizira, muyenera kuyang'ana ma adipocytes; muyenera kuyang'ana visceral adiposity. Muyenera kuwona ngati munthu uyu ndi chothandizira chotupa chamafuta am'mimba. Kodi tingatani kuti tichepetse zimenezo? Kodi kutupa kumachokera ku microbiome?
Kutsiliza
Dr. Alex Jimenez, DC, akupereka: Ngakhale impso zimatha kuchitapo kanthu pa izi, sichoncho? Monga mwina impso zawonjezera kuyamwa kwa glucose. Chifukwa chiyani? Zitha kukhala chifukwa cha kupsinjika kwa okosijeni ku impso, kapena kungakhale mu axis ya HPA, hypothalamus pituitary adrenal axis komwe mumalandira yankho la cortisol komanso kuyankha kwamanjenje kwachifundo komwe kumayambitsa kutupa ndikuyendetsa insulin m'magazi. kusokonezeka kwa shuga m'magazi? Mu Gawo 2, tikambirana apa za chiwindi. Ndiwosewera wamba kwa anthu ambiri, ngakhale alibe fulminant mafuta chiwindi matenda; Ndiwosewera wosavuta komanso wodziwika bwino kwa anthu omwe ali ndi vuto la cardiometabolic. Chifukwa chake kumbukirani, tili ndi vuto la visceral adiposity lomwe limayambitsa kutupa komanso kukana insulini ndi atherogenesis, ndipo chiwindi chili ngati munthu wosalakwa uyu yemwe wapezeka mu seweroli. Izi zimachitika nthawi zina atherogenesis imayamba.
Martinsen, Tom C et al. "Phylogeny ndi Biological Function of Gastric Juice-Microbiological Consequences Pochotsa M'mimba Acid." International Journal of Molecular Sciences vol. 20,23 6031. 29 Nov. 2019, doi:10.3390/ijms20236031
Ramsay, Philip T, ndi Aaron Carr. "Gastric acid ndi digestive physiology." Zipatala za Opaleshoni zaku North America vol. 91,5 (2011): 977-82. doi:10.1016/j.suc.2011.06.010
Kombucha ndi tiyi wotupitsa amene wakhalapo kwa zaka pafupifupi 2,000. Inakhala yotchuka ku Ulaya kumayambiriro kwa zaka za zana la 20. Lili ndi ubwino wathanzi monga tiyi, uli ndi ma probiotics, uli ndi antioxidants, ndipo ukhoza kuwononga mabakiteriya ovulaza. Malonda a Kombucha akukula pa masitolo chifukwa cha thanzi lake ndi mphamvu zake.
Kombucha
Amapangidwa ndi tiyi wakuda kapena wobiriwira, shuga, mabakiteriya athanzi, ndi yisiti. Amakometsedwa powonjezera zonunkhira kapena zipatso mu tiyi pamene akufufuma. Amafufuma kwa pafupifupi mlungu umodzi, pamene mpweya, 0.5 peresenti ya mowa, mabakiteriya opindulitsa, ndi acetic acid amapangidwa. Njira yowotchera imapangitsa kuti tiyi azitha kuyenda pang'ono. Lili ndi Mavitamini a B, antioxidants ndi probiotics, koma zakudya zopatsa thanzi zimasiyana malinga ndi zomwe zili chizindikiro ndi kukonzekera kwake.
ubwino
Mapindu ake ndi monga:
Kuwongolera chimbudzi chifukwa nayonso mphamvu kumapanga ma probiotics.
Mabakiteriya opindulitsa amadziwika kuti ma probiotics. Ma probiotics omwewa amapezeka mwa ena zakudya zofundamonga yogurt ndi sauerkraut. Ma probiotics amathandizira kudzaza matumbo ndi mabakiteriya athanzi omwe amathandizira kugaya, kuchepetsa kutupa, ndikupanga mavitamini ofunikira B ndi K. Ma probiotics amathandizira kutuluka kwamatumbo ndikuchepetsa nseru, kutupa, komanso kusagaya chakudya.
antioxidants
Ubwino wa antioxidants ndi polyphenols ndi awa:
Kuwonjezeka kwa metabolic rate
Kutsika kwa magazi
Kutsitsa cholesterol
Kupititsa patsogolo chidziwitso
Kuchepa kwa chiwopsezo cha matenda osachiritsika - matenda amtima, matenda amtundu wa 2, ndi khansa zina.
Zotsutsana ndi Bakiteriya
Njira yowotchera imabala asidi wa asidi zomwe zimawononga tizilombo toyambitsa matenda monga mabakiteriya owononga ndi yisiti, kuteteza matenda.
Mitundu yosiyanasiyana ya zokometsera ndi carbonation zachilengedwe zimatha kukhutiritsa chilakolako cha soda kapena zakumwa zina zopanda thanzi.
Chiropractic Medical Chiropractic ndi Functional Medicine Clinic imaphatikizapo zinthu zamankhwala ophatikizika ndipo imatenga njira yosiyana paumoyo ndi thanzi.. Akatswiri amawona bwino za thanzi la munthu, pozindikira kufunika kokhala ndi ndondomeko ya chithandizo chamunthu payekha kuti adziwe zomwe zikufunika kuti munthu akhale wathanzi. Gululo lipanga dongosolo lokhazikika lomwe likugwirizana ndi ndandanda ndi zosowa za munthu.
Dietitian Akufotokoza Kombucha
Zothandizira
Cortesia, Claudia et al. "Acetic Acid, chigawo chogwira ntchito cha viniga, ndi mankhwala ophera tizilombo toyambitsa matenda a tuberculocidal." mBio vo. 5,2 e00013-14. 25 Feb. 2014, doi:10.1128/mBio.00013-14
Costa, Mirian Aparecida de Campos et al. "Zotsatira za kudya kwa kombucha pamatumbo a microbiota ndi zovuta zokhudzana ndi kunenepa kwambiri: kuwunika mwadongosolo." Ndemanga zovuta mu sayansi yazakudya ndi zakudya, 1-16. 26 Oct. 2021, doi:10.1080/10408398.2021.1995321
Gaggía, Francesca, et al. "Chakumwa cha Kombucha kuchokera ku Tiyi Wobiriwira, Wakuda ndi wa Rooibos: Phunziro Lofananitsa Kuyang'ana Microbiology, Chemistry ndi Antioxidant Activity." Nutrients vol. 11,1 1. 20 Dec. 2018, doi:10.3390/nu11010001
Kapp, Julie M, ndi Walton Sumner. "Kombucha: kuwunika mwadongosolo umboni wotsimikizira za phindu la thanzi la anthu." Annals of Epidemiology vol. 30 (2019): 66-70. doi:10.1016/j.annepidem.2018.11.001
Villarreal-Soto, Silvia Alejandra, et al. "Kumvetsetsa Kuwotcha kwa Tiyi wa Kombucha: Ndemanga." Journal of Food Science vol. 83,3 (2018): 580-588. doi:10.1111/1750-3841.14068
