Zizindikiro za kusalinganika kwa mahomoni zimatha kutengera mtundu wa matenda kapena matenda omwe amayambitsa. Mwachitsanzo, zizindikiro za matenda a shuga ndi monga kunenepa, kusintha chilakolako cha chakudya, kuwonongeka kwa mitsempha, ndi vuto la maso. Ochiritsira mankhwala kwa timadzi bwino monga kupanga mahomoni m`malo mankhwala, mwachitsanzo, jakisoni insulin, chithokomiro mankhwala.
Komabe, ndi mitundu iyi yamankhwala imakhala ndi zotsatira zoyipa, monga kudalira mankhwala, zotsatira zoyipa monga sitiroko, kufooka kwa mafupa, nkhawa, mavuto obereka, khansa, ndi zina zambiri. Ndipo ndi mankhwala opangira awa, zizindikiro sizimachiritsidwa koma zimangophimba.
Mwamwayi, pali njira zopezera mahomoni mwachilengedwe. Mwachitsanzo, khalani kutali ndi mafuta ochuluka a omega-6 (safflower, mpendadzuwa, chimanga, canola, soya, ndi mtedza). M'malo mwake, gwiritsani ntchito magwero olemera a omega-3's (nsomba zakutchire, flaxseed, chia njere, walnuts, ndi nyama zodyetsedwa ndi udzu).
Zikafika ku matupi athu, machitidwe ambiri ogwirira ntchito amathandiza thupi kuwongolera kutentha kwake, kupereka kuyenda ndi kukhazikika pamene likuyenda, ndi kuteteza mwiniwake ku tizilombo toyambitsa matenda zomwe zimalowa mkati kuti ziwononge. Chimodzi mwa machitidwe omwe amathandiza thupi ndi dongosolo la endocrine, yomwe imapanga mahomoni ambiri kuti thupi lizigwira ntchito bwino. The chithokomiro, kachiwalo kakang’ono kooneka ngati gulugufe m’munsi mwa khosi, kamatulutsa mahomoni m’thupi. Chithokomiro chimathandizira kupanga mahomoni; Komabe, pamene tizilombo toyambitsa matenda zimakhudza kupanga mahomoni m'thupi, zingayambitse ku kupweteka kwa minofu ndi mafupa ndi kukanika. Nkhani ya lero ikuwunika momwe chithokomiro chimapangitsira mahomoni, momwe kusagwirizana kwa mahomoni kumayenderana ndi ululu wa minofu ndi mafupa, komanso momwe chithandizo cha MET chingathandizire kubwezeretsa kusagwirizana kwa mahomoni kuti asakhudze thupi m'tsogolomu. Timagwiritsa ntchito zidziwitso za odwala athu kwa othandizira ovomerezeka omwe amagwiritsa ntchito njira zochiritsira zofewa monga MET kuti tichepetse kupweteka kwa minofu ndi mafupa okhudzana ndi kusalinganika kwa mahomoni. Timalimbikitsa odwala powatumiza kwa azachipatala omwe amagwirizana nawo malinga ndi momwe akudwala komanso kuchirikiza mfundo yakuti maphunziro ndi njira yabwino kwambiri yofunsa opereka chithandizo mafunso osangalatsa kwambiri pakuvomereza kwa wodwalayo. Dr. Alex Jimenez, DC, akuphatikiza mfundozi ngati ntchito yophunzitsa. chandalama
Kodi Chithokomiro Chimapanga Bwanji Ma Hormone?
Kodi mumamva kufooka kwa minofu kapena kupweteka kwa ziwalo zina za thupi lanu? Kodi mukumva kutopa mutayenda mtunda waufupi? Kapena mumadzimva kukhala aulesi tsiku lonse? Anthu ambiri akakumana ndi zovuta zambiri izi, zitha kukhala chifukwa cha kusalinganika kwa mahomoni awo kuchokera ku chithokomiro chawo. Zikafika m'thupi, dongosolo la endocrine ndilomwe limatsogolera kupanga mahomoni osiyanasiyana kuti thupi lithandizire kuwongolera njira zonse zamoyo. Chimodzi mwa ziwalo zofunika kwambiri za dongosolo la endocrine ndi chithokomiro. Kafukufuku akuwonetsa kuti chithokomiro ndi endocrine gland yomwe ili kumunsi kwa khosi lakunja la thupi ndipo imapanga mahomoni a T4 ndi T3 kuti thupi lizigwira ntchito bwino. Mahomoni a chithokomiro amakhudza ziwalo zambiri zofunika ndi minyewa ya thupi chifukwa amathandiza pa izi:
Kutulutsa kwa Cardio ndi kuchuluka kwa mtima wopumula
Kumalimbikitsa kupuma kupuma ndi dongosolo lamanjenje
Amagwira ntchito pa uchembere wabwino ndi ntchito zina za endocrine
Maphunziro owonjezera awululira kuti mahomoni a chithokomiro amathandiza kuwongolera kagayidwe ka thupi, kakulidwe, ndi magwiridwe antchito ena amthupi pomwe amakhala ndi ubale wamba ndi axis ya HPT (hypothalamic-pituitary-thyroid). Zomwe ubalewu umachita ndikuti umawonetsetsa kuti thupi likugwira ntchito moyenera pamalo aliwonse. Komabe, tizilombo toyambitsa matenda tikamayamba kukhudza kupanga mahomoni a chithokomiro, kungayambitse kusalinganika kwa mahomoni ndipo kumayambitsa zizindikiro zosafunika zowawa m'zigawo zofunika kwambiri ndi minofu ya minofu.
Kusalinganika kwa Hormone & Kupweteka kwa Minofu
Pamene tizilombo toyambitsa matenda tosafunikira timagwirizanitsa ndi zinthu zachilengedwe zomwe zimakhudza thupi, zimatha kuyambitsa zizindikiro zowawa zomwe zingayambitse kupweteka kwa minofu. M'bukuli, "Clinical Applications of Neuromuscular Techniques," lolembedwa ndi Dr. Judith Walker DeLany, LMT, ndi Leon Chaitow, ND, DO, adanena kuti pali kugwirizana pakati pa kusalinganika kwa mahomoni ndi ululu wa musculoskeletal monga pali zinthu zambiri zachilengedwe zomwe zingatheke. zimakhudza kuchuluka kapena kuchepa kwa mahomoni omwe amapangidwa kuchokera ku chithokomiro. Bukuli limatchulanso kuti zina mwa zizindikiro za kusowa kwa mahomoni a chithokomiro ndi monga:
Khungu louma ndi tsitsi lochepa thupi
Kutopa kwachilendo
Kuwonjezeka kosadziwika bwino
Kupweteka kwa minofu
Kusokonezeka maganizo
Pamene thupi likulimbana ndi kusalinganika kwa mahomoni komwe kumakhudzana ndi kupweteka kwa minofu ndi mafupa, maphunziro amawulula kuti zizindikiro za kutopa, nkhawa, kukwiya, komanso kuwonjezereka kwa okosijeni kungapangitse minofu ya minofu ndi mitsempha kukhala yofooka ndikupangitsa kuti pakhale ngozi zambiri pamene thupi likuyenda. Mpaka pano, kusalinganika kwa mahomoni kungayambitse kupweteka kwa minofu ndi mafupa okhudzana ndi mfundo za myofascial trigger point ndi kuchepa kwa minofu.
Kupeza Hormonal Harmony- Kanema
Kodi mwakhala mukumva kupweteka kwa minofu kapena mafupa? Kodi nthawi zambiri mumada nkhawa kapena kukwiya nthawi zonse? Kapena mwaona kuti mumakhudzidwa kwambiri ndi kuzizira? Zambiri mwazinthu zonga zowawazi ndizizindikiro ndi zizindikiro zomwe zimagwirizanitsidwa ndi kusalinganika kwa mahomoni m'thupi ndipo zimatha kuyambitsa kupweteka kwaminyewa. Thupi limafunikira mahomoni kuti athandizire kuwongolera kutentha kwa thupi, kuwongolera kagayidwe kachakudya m'thupi, ndikuthandizira kulimbikitsa dongosolo la endocrine ndi thupi. Mahomoni amatulutsidwa kuchokera ku chithokomiro ndipo amapita ku minofu yofunika, ziwalo, ndi minofu kudzera m'magazi kuti athandize ndikuthandizira gawo lililonse la thupi kuti ligwire ntchito bwino. Tizilombo toyambitsa matenda tikayamba kusokoneza kupanga kwa mahomoni, chithokomiro chimatha kutulutsa kwambiri kapena kutulutsa pang'onopang'ono kutulutsa kwa timadzi ndikupangitsa kuti pakhale ngozi zambiri mthupi ndi minofu ndi mafupa. Mwamwayi, pali njira zambiri zoyendetsera mahomoni ndi kuchepetsa zotsatira za ululu wa musculoskeletal. Vidiyo yomwe ili pamwambayi ikufotokoza kuti kuwonjezera mavitamini ena, kudya zakudya zopatsa thanzi, zopatsa thanzi, komanso kuchita masewera olimbitsa thupi komanso kugona mokwanira kungathandize kuchepetsa kupanga mahomoni ndi kuchepetsa zotsatira za ululu wa minofu ndi mafupa. Mankhwala osiyanasiyanawa amatha kuphatikizidwa ndi chithandizo chothandizira kukonzanso thupi ndikulibwezeretsa mwachibadwa.
MET Therapy Kubwezeretsa Kusamvana kwa Ma Hormone
Mankhwala ambiri omwe alipo amatha kuchepetsa zotsatira za kusalinganika kwa mahomoni okhudzana ndi ululu wa minofu ndi mafupa. Mankhwala monga MET (njira za mphamvu za minofu) amalola akatswiri ambiri opweteka kuti agwiritse ntchito njira za minofu yofewa kuti achepetse zizindikiro zopweteka ndipo zidzathandiza kuti thupi lizibwezeretsanso mwachibadwa. Kafukufuku wasonyeza kuti mankhwala ochizira minofu yofewa monga MET amatha kuchepetsa ululu, kupititsa patsogolo ntchito ya thupi, ndi kuchepetsa kulemala. Thandizo la MET likhoza kuphatikizidwa ndi zakudya zopatsa thanzi, mankhwala ochizira mahomoni, ndi njira zogwirira ntchito zolimbitsa thupi zomwe zingathandize kupanga mahomoni mu chithokomiro. Munthu akayamba kupita kuchiza matenda aliwonse omwe amakhudza thupi lawo, zimapangitsa kuti anthuwa azikumbukira zomwe zikuchitika m'matupi awo ndikupanga kusintha kwakung'ono ku thanzi lawo komanso thanzi lawo.
Kutsiliza
Pankhani yosunga thanzi la thupi ndi thanzi, ndikofunikira kuonetsetsa kuti tizilombo toyambitsa matenda tisayambe kukhudza kupanga mahomoni a chithokomiro. Chithokomiro ndi kachithokomiro kakang'ono kamene kamakhala m'munsi mwa khosi kamene kamatulutsa timadzi tomwe timatulutsa timadzi tambirimbiri. Chithokomiro chikatulutsa mahomoni ambiri m'ziwalo, minofu ndi minofu, zimatha kuyambitsa zizindikiro zowawa zomwe zimakhudza dongosolo la thupi ndipo zimatha kuyambitsa matenda a minofu ndi mafupa. Kuchiza monga chithandizo cha MET kuphatikiza zakudya zonse zopatsa thanzi komanso masewera olimbitsa thupi kumatha kuchepetsa zotsatira za kusalinganika kwa mahomoni komwe kumakhudzana ndi matenda a minofu ndi mafupa. Kuphatikizana kodabwitsa kumeneku kumapangitsa kuti thupi lichiritse mwachibadwa ndipo limalola munthu kukhala wopanda ululu.
Zothandizira
Armstrong, Maggie, et al. "Physiology, Thyroid Function - Statpearls - NCBI Bookshelf." Mu: StatPearls [Intaneti]. Chilumba cha Treasure (FL), 13 Mar. 2023, www.ncbi.nlm.nih.gov/books/NBK537039/.
Chaitow, Leon, ndi Judith Walker DeLany. Ntchito Zachipatala za Neuromuscular Techniques. Churchill Livingstone, 2003.
Day, Joseph M, ndi Arthur J Nitz. "Zotsatira za Njira Zopangira Mphamvu za Minofu pa Kulumala ndi Kuchuluka Kwa Ululu mwa Anthu Omwe Ali ndi Ululu Wochepa Kwambiri." Journal of Sport Rehabilitation, May 2012, pubmed.ncbi.nlm.nih.gov/22622384/.
Shahid, Muhammad A, et al. "Physiology, Thyroid Hormone - StatPearls - NCBI Bookshelf." Mu: StatPearls [Intaneti]. Chilumba cha Treasure (FL), 8 May 2022, www.ncbi.nlm.nih.gov/books/NBK500006/.
VandeVord, Pamela J, et al. "Kusakhazikika kwa Hormonal Imbalance ndi Adipose Redistribution Kumalumikizidwa ndi Hypothalamic Neuropathology Pambuyo Kuwonekera Kwambiri." Journal ya Neurotrauma, 1 Jan. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4700394/.
Dr. Alex Jimenez, DC, akupereka momwe angayang'anire zizindikiro za kusalinganika kwa mahomoni mwa amuna ndi momwe njira zosiyanasiyana zothandizira, monga chisamaliro cha chiropractic, zingathandize kuyendetsa ntchito ya mahomoni m'thupi. Timawatsogolera odwala kwa othandizira ovomerezeka omwe amapereka chithandizo chothandizira cha mahomoni chomwe chingabwezeretse magwiridwe antchito a thupi. Timavomereza wodwala aliyense ndi zizindikiro zake powatumiza kwa azachipatala omwe timalumikizana nawo kutengera momwe akudwala kuti amvetsetse zomwe akukumana nazo. Timamvetsetsa kuti maphunziro ndi njira yabwino kwambiri yofunsa opereka athu mafunso osiyanasiyana omwe amagwira ntchito pakudziwa kwa wodwalayo. Dr. Jimenez, DC, amagwiritsa ntchito mfundoyi ngati ntchito yophunzitsa. chandalama
Hormone Kusalinganika
Dr. Alex Jimenez, DC, akupereka: Lero, tidzakhala tikuyang'ana momwe tingayang'anire zizindikiro za kusalinganika kwa mahomoni mwa amuna komanso momwe chisamaliro cha chiropractic chingathandizire ndi zizindikiro zokhudzana ndi kusalinganika kwa mahomoni. Tiyenera kumvetsetsa ma subtypes a kuchepa kwa mahomoni kuti tithandizire njira zoyenera zochizira monga chisamaliro cha chiropractic. Chifukwa chake pankhani ya mahomoni m'thupi, ndikofunikira kudziwa momwe mahomoni amagwirira ntchito m'thupi komanso zomwe zimachitika ngati comorbidities zimagwirizana ndi kusalinganika kwa mahomoni. Kusalinganika kwa mahomoni m'thupi lachimuna kungayambitse zotsatira za physiologic za testosterone yotsika yolumikizana ndi zosokoneza.
Gwirani ntchito ndi mahomoni ena (insulin, DHEA, cortisol)
Thandizani machitidwe akuluakulu a thupi
Pankhani ya thupi lachimuna, mahomoni awiri akuluakulu, androgen ndi testosterone, angathandize ndi chidziwitso. Komabe, thupi likayamba kukalamba mwachibadwa, njira ya mahomoni imayamba kuchepa mu thupi lachimuna ndipo zimayambitsa matenda aakulu kuti ayambe kuyambitsa mavuto m'thupi. Izi zikachitika, zimatha kupangitsa munthuyo kumva ululu ndikusokoneza zochita za tsiku ndi tsiku.
Zosokoneza Zachilengedwe & Miyezo Yotsika ya Testosterone
Dr. Alex Jimenez, DC, akupereka: Popeza kuti zosokoneza zambiri za chilengedwe zimatha kukhudza thupi ndikuyambitsa kusalinganika kwa mahomoni, zingayambitse zizindikiro zosiyanasiyana muzotsatira zambiri zoyesa pamene odwala akuyesedwa ndi madokotala awo oyambirira. Zizindikiro za kutopa kosatha, chifunga chaubongo, kukhumudwa, kuchuluka kwa minofu, komanso kuchepa kwa libido kumalumikizana ndi kusowa kwa testosterone ndipo zimatha kupangitsa kuti thupi lisagwire ntchito. Ndipo ngati pali kusagwira bwino ntchito kwa mahomoni m'thupi, kungayambitsenso kutupa komwe kumayenderana ndi kusowa kwa mahomoni. Pamene kutupa kumayamba kukhudza minofu ndi ziwalo za thupi lachimuna, kungayambitse nkhani zomwe zimakhudza msana, chiuno, miyendo, mapewa, ndi khosi zomwe zingayambitse kuyenda kochepa, kutopa kwa minofu, kuwonjezeka kwa mafuta a thupi, ndi kuchepa kwa mafupa a mafupa. kachulukidwe.
Magulu otsika a testosterone m'thupi amatha kulumikizana ndi zomwe zidalipo kale zomwe zimagwirizana ndi metabolic syndrome yokhudzana ndi hypogonadism. Hypogonadism ndi pamene ziwalo zoberekera za thupi zimapanga mahomoni ochepa kuti agwire ntchito yogonana. Hypogonadism imatha kukhudza pafupifupi 30% ya amuna onse azaka zapakati pa 40-79. Kufikira pamenepo, zimapangitsa kuti thupi lachimuna lipange mahomoni ochulukirapo a leptin ndipo zimatha kusokoneza ubongo zikafika pakutulutsa mahomoniwa m'thupi. Pa mulingo wa hypothalamic wa gonadotropin-release hormones, tawonjezera kukhudzika ku hypothalamus ku malingaliro olakwika ochokera ku androgens. Izi zitha kukhala zinthu zambiri zomwe zingayambitse kuchepa kwa testosterone yamwamuna:
zakudya
kupanikizika
Toxin
kufooka kwa mafupa
Kuchuluka kwa tsitsi kumachepa
Kusokonekera kwa Erectile
Andropause
Ziwalo zoberekera zikatulutsa mahomoni ochepa, amatha kupanga andropause ndikupangitsa kuti ma testosterone achepe. Andropause ndi mtundu wachimuna wa kusintha kwa akazi kwa akazi, zomwe zimatha kubweretsa zovuta zina monga dementia, Alzheimer's, shuga, ndi metabolic syndrome. Kodi metabolic syndrome imalumikizidwa bwanji ndi andropause ikafika pakusakwanira kwa mahomoni? Chabwino, kuchepa kwa testosterone m'thupi kumatha kukulitsa milingo ya insulini, zomwe zimapangitsa kuti insulini isakane, zomwe zimapangitsa kuti BMI ichuluke m'thupi. Kufikira pamenepo, zovuta monga kupsinjika kwanthawi yayitali zimatha kutsitsa DHEA ndi ma hormone a testosterone, omwe amatha kukulitsa milingo ya insulin ndikuyambitsa zowawa zambiri m'thupi.
Chisamaliro cha Chiropractic & Hormones
Dr. Alex Jimenez, DC, akupereka: Tsopano zonse sizinataye, popeza pali njira zowonjezera kupanga mahomoni m'thupi. Anthu ambiri amatha kuchita masewera olimbitsa thupi pafupipafupi kuti achepetse kuchuluka kwa cortisol ndi insulin pomwe akukulitsa milingo ya testosterone. Njira ina yowonjezerera kusokonezeka kwa mahomoni ndi kupita kuzinthu zosiyanasiyana zochiritsira monga chisamaliro cha chiropractic kuti zithandize kuchepetsa zina mwa zizindikiro zokhudzana ndi kusalinganika kwa mahomoni. Tsopano chisamaliro cha chiropractic chingagwirizane bwanji ndi kusalinganika kwa mahomoni? Kodi sikusintha kwamanja kumbuyo?
Chodabwitsa kwambiri chisamaliro cha chiropractic ndichoposa kungoyendetsa msana pamene uli mu subluxation. Monga tanenera kale, kusalinganika kwa mahomoni kungayambitse kupsinjika kwa minofu ndi mafupa omwe amatha kupsa ndikuyambitsa mavuto aakulu. Pamene kusalinganika kwa mahomoni m'thupi kumayambitsa kupanga testosterone yochepa, kungayambitse kupsinjika kwa magulu a minofu ndikukhudza ziwalo. Kufikira pamenepo, thupi lidzakhala likumva kupweteka kosalekeza kapena kugonja ku zovulala zosiyanasiyana. Choncho, kuphatikiza chisamaliro cha chiropractic monga gawo la chithandizo kungathandize kusintha thupi la musculoskeletal dongosolo ndi momwe mungathanirane ndi kupsinjika maganizo, kulola dongosolo la mitsempha, kumene mahomoni amatumizidwa kumadera osiyanasiyana m'thupi, kuti azigwira ntchito bwino ndikugwira ntchito bwino. Chisamaliro cha Chiropractic chimapangitsa kuti thupi likhale lopanda ululu chifukwa cha kusokonezeka kwa minofu yokhudzana ndi kusalinganika kwa mahomoni ndipo ikhoza kuphatikizidwa ndi mankhwala ena.
Kutsiliza
Kugwiritsira ntchito ndi kuphatikiza chisamaliro cha chiropractic ndi mankhwala a mahomoni amatha kulola kuti thupi lizigwira ntchito moyenera komanso kuchepetsa zizindikiro zopweteka zomwe zingakhudze minofu ndi ziwalo za thupi. Chisamaliro cha Chiropractic kuphatikiza ndi zakudya zopatsa thanzi zomwe zimathandiza kuwongolera mahomoni komanso chithandizo chamankhwala zimathandizira kuti ma hormoni am'thupi akhale abwinobwino. Kufikira pamenepo, mankhwala ophatikizanawa amatha kupititsa patsogolo kukula kwa minofu ndi kuchepetsa zizindikiro zomwe zimagwirizanitsidwa ndi kusamvana kwa mahomoni zomwe zingayambitse kupweteka kwa minofu ndi mafupa ogwirizana ndi zina zomwe zakhalapo kale zokhudzana ndi mahomoni.
Dr. Alex Jimenez, DC, akuwonetsa momwe zomwe zimayambitsa ndi zotsatira za chiopsezo cha cardiometabolic zingakhudzire thanzi la munthu. Cardiometabolic syndrome imatha kukhudza munthu aliyense kudzera m'mayendedwe amoyo ndikuyambitsa zizindikiro zowawa zomwe zingakhudze thanzi lawo. Timatumiza odwala kwa othandizira ovomerezeka omwe amapereka chithandizo chamtima chokhudzana ndi metabolic syndrome kuti athetse zovuta zomwe zimakhudza thupi ndikuwonetsetsa kuti wodwalayo ali ndi thanzi labwino kudzera muzamankhwala osiyanasiyana. Timavomereza wodwala aliyense powatumiza kwa azachipatala omwe timalumikizana nawo malinga ndi momwe alili kuti amvetsetse bwino zomwe akuchita nazo moyenera. Tikumvetsetsa kuti maphunziro ndi njira yabwino kwambiri yofunsa opereka athu mafunso osiyanasiyana ovuta kuti wodwalayo adziwe. Dr. Jimenez, DC, amagwiritsa ntchito chidziwitsochi ngati ntchito yophunzitsa. chandalama
Zomwe Zimayambitsa & Zotsatira Za Kuopsa kwa Cardiometabolic
Dr. Alex Jimenez, DC, akupereka: Tsopano, tikulowa m'nthawi yatsopanoyi, anthu ambiri akuyesera kupeza njira zothanirana ndi chiopsezo cha cardiometabolic. Chifukwa chake mu chiwonetserochi, tiwona wakupha nambala wani m'maiko ambiri amakono; matenda amtima amatanthauzidwa ngati gulu la zinthu zomwe zimakhudza mtima. Zinthu zambiri zimagwirizanitsidwa ndi matenda amtima omwe amakumana ndi metabolic syndrome. Mawu akuti cardiometabolic akuwonetsa kuti tikambirana zazambiri kuposa chiopsezo cha mtima.
Cholinga ndicho kupeza malingaliro pa zokambirana zakale zokhudzana ndi chiopsezo cha mtima chokhudzana ndi kayendedwe ka magazi. Tonse tikudziwa kuti kayendedwe ka thupi, kupuma, ndi mafupa ali ndi zigawo zosiyana zomwe zimakhala ndi ntchito zosiyanasiyana kuti thupi ligwire ntchito. Vuto ndilakuti thupi limagwira ntchito m'machitidwe osiyanasiyana osadalirana. Zimabwera palimodzi ndikulumikizana ngati ukonde.
The Circulatory System
Dr. Alex Jimenez, DC, akupereka: Choncho dongosolo la kayendedwe ka magazi limathandiza kunyamula mitsempha ya magazi ndi kulola mitsempha ya mitsempha kunyamula maselo ndi zinthu zina monga mahomoni kuchokera kumalo ena kupita kwina. Chitsanzo chingakhale ma receptor anu a insulin omwe amasuntha zidziwitso mthupi lanu lonse komanso zolandilira shuga zomwe zimagwiritsidwa ntchito ngati mphamvu. Ndipo mwachiwonekere, mitundu ina yonse ya olankhulana imayang'anira momwe zoyendera zimachitikira m'thupi. Tsopano thupi si lotsekedwa lokhazikika dera lolumikizidwa kudzera kunja. Zinthu zambiri zimatha kukhudza thupi mkati ndi kunja komwe kumatha kukhudza khoma la arterial ndikuyambitsa zovuta zomwe zimakhudza dongosolo lamtima. Tsopano, chikuchitika ndi chiyani pakhoma lamtsempha lomwe limayambitsa zinthu zambirimbiri m'thupi?
Zinthu zikayamba kukhudza khoma lamkati mkati, zimatha kupangitsa kuti plaque ikhale m'mitsempha yamagazi komanso ngakhale kukhudza kukhulupirika kwa makoma akunja a mitsempha. Izi zikachitika, LDL kapena low-density lipoprotein imatha kukula ndikupangitsa kuchuluka kwa cholesterol. Kufikira pamenepo, thupi likakhala ndi zizolowezi zoipa, zimatha kupangitsa kuti thupi likhale pachiwopsezo chachikulu cha mtima. Pamene thupi likugwira ntchito ndi matenda amtima omwe ali pachiwopsezo chachikulu, amatha kuyambitsa kuthamanga kwa magazi, shuga, kapena metabolic syndrome. Izi zimapangitsa kuti thupi likhale ndi kupweteka kwa minofu ndi mafupa kumbuyo, m'khosi, m'chiuno, ndi pachifuwa, kutchula zochepa chabe, ndipo zingayambitse munthu kulimbana ndi kutupa m'matumbo, mafupa, ndi minofu.
Zinthu Zogwirizana ndi Cardiometabolic Risk Factors
Dr. Alex Jimenez, DC, akupereka: Koma chochititsa chidwi n’chakuti, sipanafike posachedwapa pamene mabungwe amene amalamulira mulingo wathu wa kasamalidwe kathu akusamalira izi mozama, ponena kuti zikufunika kukhala mbali ya malangizowo chifukwa deta imaonekera kwambiri kuti mmene moyo wa munthu umakhudzira thanzi lake. Deta imatha kutengera momwe zakudya zina, monga zakudya zaku Mediterranean, zingasinthire zizolowezi zamunthu. Momwe kupsinjika kumayenderana ndi matenda a cardiometabolic. Kapenanso kuchuluka kwa masewera olimbitsa thupi kapena kugona komwe mukugona. Zinthu zachilengedwe izi zimagwirizana ndi momwe ziwopsezo za cardiometabolic zimakhudzira thupi. Podziwitsa odwala zomwe zikuchitika ndi matupi awo, amatha kusintha pang'ono ku zizolowezi zawo za moyo. Tsopano tiyeni tiwone momwe zakudya zingakhudzire munthu yemwe ali ndi chiopsezo cha cardiometabolic.
Pokambirana za zakudya, anthu ambiri amatha kuona zotsatira za zakudya zamtundu wa ku America komanso momwe zingayambitse kuwonjezeka kwa caloric pakati pa adiposity. Pokambirana za zakudya, ndi bwino kuzindikira zomwe munthuyo akudya, zomwe zimayambitsa chiopsezo cha cardiometabolic m'matupi awo. Madokotala amagwira ntchito limodzi ndi akatswiri a kadyedwe kuti apeze yankho loti akwaniritse kuchuluka kwa mapuloteni omwe munthu aliyense amafunikira, kuchuluka kwa masamba ndi zipatso zomwe atha kudya, komanso zomwe zimawawa kapena zovuta zomwe zingapewe. Kufikira pamenepo, kudziwitsa odwala za kudya zakudya zopatsa thanzi, zopatsa thanzi komanso zopatsa thanzi kudzawathandiza kumvetsetsa zomwe amaika m'matupi awo komanso momwe angasinthire zotsatira zake. Tsopano munthu aliyense ndi wosiyana monga momwe zakudya zina zimakhalira kwa anthu ena pamene ena satero, ndikofunikanso kuti polangiza odwala za zomwe akudya ndi kudya komanso za nthawi. Anthu ena amasala kudya kuti ayeretse matupi awo pochotsa poizoni ndikulola maselo am'thupi kupeza njira zosiyanasiyana zogwiritsira ntchito mphamvu.
Momwe Zakudya Zakudya Zimagwirira Ntchito Mu Cardiometabolic Syndrome
Dr. Alex Jimenez, DC, akupereka: Koma kodi mumadziwa kuti kuchuluka kwa zopatsa mphamvu muzakudya zokhazikika zaku America kumatha kuwononga matumbo athu, ndikupangitsa kuti matumbo asapitirire, ndikupanga zochitika zodziwika bwino zomwe zimatchedwa metabolic endotoxemia zomwe zimayambitsa kutupa? Ubwino ndi kuchuluka kwa zakudya zimatha kusokoneza ma microbiome athu, zomwe zimatsogolera ku dysbiosis ngati njira ina yotupa. Ndipo kotero mumapeza chitetezo chamthupi ichi ndi kusokoneza komwe kumapangitsa kusamba kosalekeza komwe majini anu akusamba. Kutupa kumatha kukhala kwabwino kapena koyipa kutengera kuopsa kwa zomwe zikuchitika m'thupi. Ngati thupi likuvulala chifukwa chovulala kapena likukumana ndi zovuta zazing'ono, kutupa kumatha kuchiritsa. Kapena ngati kutupa kuli koopsa, kungachititse kuti khoma la m'mimba lipse n'kutulutsa poizoni ndi tizilombo toyambitsa matenda m'thupi lonse. Izi zimadziwika kuti matumbo otayirira, omwe angayambitse kupweteka kwa minofu ndi mafupa okhudzana ndi kunenepa kwambiri. Chifukwa chake tikufuna kukulitsa zokambiranazo pazakudya chifukwa kunenepa kwambiri kumakhudza zakudya zopanda thanzi. Nthawi zambiri amati ndife odyetsedwa komanso osadyetsedwa bwino ngati anthu. Chifukwa chake tikufuna kuti tithe kuchepetsa mayendedwe a kunenepa moyenera. Ndipo tikufuna kubweretsa zokambirana zazikuluzikulu zokhudzana ndi thanzi labwino. M'kupita kwa zaka, anthu ambiri amadziwa bwino momwe chilengedwe chawo komanso moyo wawo zimakhudzira matenda amtima kapena mtima.
Tiyenera kuzindikira kuti thupi la munthu limakhala mu chikhalidwe cha chikhalidwe ichi chomwe chimatsimikizira kuthekera kwa thanzi. Tikufuna kuchititsa odwala kuti adziwitse zamphamvu kwambiri zolimbana ndi kutupa m'miyoyo yawo komanso momwe amasankhira moyo wawo. Ndipo sitikukambirana za mafashoni monga kuvala spandex ndikupita ku masewera olimbitsa thupi kamodzi pamwezi; tikukamba za mayendedwe atsiku ndi tsiku komanso momwe mungachepetsere khalidwe lokhala chete lokhudzana ndi matenda a cardiometabolic syndrome. Tidakambirana momwe ngakhale kukhudzidwa kwa kupsinjika kumatha kulimbikitsa atherosulinosis, arrhythmias, ndi kagayidwe kachakudya m'thupi ndikuyambitsa zovuta zosiyanasiyana zomwe zingakhudze thanzi la munthu.
Kupanikizika & Kutupa Udindo Mu Thupi
Dr. Alex Jimenez, DC, akupereka: Kupsinjika maganizo, monga kutupa, kungakhale kwabwino kapena koipa, malingana ndi mmene zinthu zilili. Chifukwa chake kupsinjika kumatha kukhudza kuthekera kwa munthu kuti agwire ntchito padziko lapansi pamene tikulowa muzovuta za biology zomwe zimachitika chifukwa cha kupsinjika kwakukulu komanso kosatha komanso momwe tingathandizire odwala athu. Tiyenera kumvetsetsa kuti tiyenera kudziyika tokha mu nsapato za odwala athu poganizira momwe tingachepetsere kupsinjika kwakanthawi kuti tichepetse chiopsezo cha cardiometabolic ndikuwongolera moyo wabwino.
Chifukwa chake posakhazikika pakuyesa chilichonse nthawi imodzi kuti muchepetse chiopsezo cha cardiometabolic, kutenga zonse zomwe timaphunzira ndikuziphatikiza pang'onopang'ono m'miyoyo yathu yatsiku ndi tsiku zitha kukhudza kwambiri momwe timawonekera, momwe timamvera komanso zomwe timadya zimatha kusintha thanzi lathu. -kukhala. Dr. David Jones anati, “Ngati zonse zimene timachita ndi kulankhula za zimenezi ndipo zonse zimene timachita n’kudziŵa zimenezi, sizimagwira ntchito yonse imene tili nayo monga cholinga kwa odwala athu.”
Tiyenera kudzichotsa tokha kuchoka pa siteji yodziwa kupita ku siteji yochitira chifukwa ndipamene zotsatira zidzachitika. Chifukwa chake poyang'ana chithunzi chachikulu, titha kubwezeretsa thanzi lathu ku matenda a cardiometabolic poyang'ana komwe vuto likuchitika m'matupi athu ndikupita kwa akatswiri osiyanasiyana omwe amatha kupanga dongosolo lamankhwala kuti achepetse kupsinjika ndi kutupa m'matupi athu komwe kungathe. kuchepetsa zotsatira za cardiometabolic syndrome.
Kutsiliza
Dr. Alex Jimenez, DC, akupereka: Chifukwa chake ngati anthu ambiri akukumana ndi ziwopsezo zamtima, amakhala ndi machitidwe odziwika bwino awa, kusokonekera kwa biology, kaya kukhudzana ndi kutupa, kupsinjika kwa okosijeni, kapena kusokonekera kwa insulin, zonse zikuchitika pansi. . Muzamankhwala ogwira ntchito, tikufuna kupita kumtunda munyengo yatsopanoyi ya thanzi la cardiometabolic. Tikufuna kupititsa patsogolo chilengedwe ndi moyo kuti ziwononge biology yadongosolo kuti zikhale bwino kuti athe kulola kuthekera kwa epigenetic kwa wodwala kukhala pachiwonetsero chake chathanzi.
Popereka zida zoyenera kwa odwala, madokotala ambiri ogwira ntchito zamankhwala amatha kuphunzitsa odwala awo momwe angabwezeretse thanzi lawo pang'ono nthawi iliyonse. Mwachitsanzo, munthu akulimbana ndi kupsinjika maganizo kosatha, kumayambitsa kuuma kwa khosi ndi msana, zomwe zimapangitsa kuti asathe kuyendayenda. Madokotala awo amatha kupanga dongosolo lophatikiza kusinkhasinkha kapena kutenga kalasi ya yoga kuti muchepetse nkhawa m'matupi awo ndikukumbukira. Chifukwa chake popeza chidziwitso chofunikira chachipatala chokhudza momwe munthu akuvutikira ndi cardiometabolic, madotolo ambiri amatha kugwira ntchito limodzi ndi othandizira azachipatala kuti apange dongosolo lachithandizo lothandizira aliyense amene akudwala matenda a cardiometabolic.
Dr. Alex Jimenez, DC, akuwonetsa momwe adrenal insufficiencies ingakhudzire kuchuluka kwa mahomoni m'thupi. Mahomoni amagwira ntchito yofunika kwambiri powongolera kutentha kwa thupi komanso kugwira ntchito kwa ziwalo zofunika kwambiri ndi minofu. Mndandanda wa magawo awiriwa uwunika momwe kusakwanira kwa adrenal kumakhudzira thupi ndi zizindikiro zake. Mu gawo 2, tiwona chithandizo cha adrenal insufficiencies ndi kuchuluka kwa anthu omwe angaphatikizepo mankhwalawa paumoyo wawo komanso thanzi lawo. Timatumiza odwala kwa othandizira ovomerezeka omwe amaphatikizapo mankhwala a mahomoni omwe amachepetsa zovuta zosiyanasiyana zomwe zimakhudza thupi ndikuonetsetsa kuti wodwalayo ali ndi thanzi labwino komanso thanzi. Timayamikila wodwala aliyense powatumiza kwa azachipatala omwe amalumikizana nawo malinga ndi zomwe wadwala pakafunika kuti timvetsetse bwino zomwe akumva. Tikumvetsetsa kuti maphunziro ndi njira yabwino kwambiri yofunsa mafunso otisamalira mosiyanasiyana malinga ndi zomwe wodwalayo akufuna komanso kudziwa. Dr. Alex Jimenez, DC, amagwiritsa ntchito chidziwitsochi ngati ntchito yophunzitsa. chandalama
Kodi Adrenal Insufficiencies Ndi Chiyani?
Dr. Alex Jimenez, DC, akupereka: Zinthu zambiri zingakhudze thupi, kaya kadyedwe, thanzi labwino, kapena zizoloŵezi za moyo zonse zimathandizira kuti mahomoni apitirize kugwira ntchito m’thupi. Masiku ano, tigwiritsa ntchito njira zodziwika bwino za cortisol zomwe odwala amakhalapo akapita kukayezetsa tsiku ndi tsiku. Odwala ambiri nthawi zambiri amabwera ndikufotokozera madokotala awo kuti akudwala matenda a adrenal chifukwa zizindikiro zosiyanasiyana zimagwirizanitsidwa ndi magawo osiyanasiyana a adrenal dysfunction kapena HPA kukanika. Tsopano adrenal kukanika kapena hypothalamic pituitary adrenal (HPA) kukanika ndi pamene adrenal tiziwalo timene timatulutsa timadzi ta adrenal sakupanga timadzi tokwanira kulamulira thupi. Izi zimapangitsa kuti thupi lidutse magawo osiyanasiyana a adrenal dysfunction ngati silinachiritsidwe motere, zomwe zimapangitsa kuti thupi lizitha kuthana ndi kupweteka kwa minofu ndi mafupa omwe munthu sanachite nawo moyo wake wonse.
Madokotala ambiri ndi othandizira azaumoyo amagwiritsa ntchito njira mwadongosolo yomwe ingathandize anthu ambiri kuthana ndi vuto la adrenal m'matupi awo kapena ayi. Lero, tikambirana za ubale womwe ulipo pakati pa mahomoni achikazi ndi kusokonezeka kwamalingaliro komwe kumakhudzana ndi vuto la adrenal. Zikafika pakusokonekera kwa adrenal komwe kumalumikizidwa ndi mahomoni, anthu ambiri nthawi zambiri amalandila mankhwala amatenda amisala monga matenda a bipolar kapena kukhumudwa pamene mahomoni awo sali bwino. Kusalinganika kwa mahomoni kukayamba kukhudza amayi omwe ali ndi zaka zoyambira makumi asanu chifukwa chosiya kusamba, vuto lamalingaliro limakula ndikuyambitsa zovuta zina zambiri zomwe zingakhudze mahomoni awo ndi matupi awo.
Kukanika kwa Adrenal Kumakhudza Thupi
Dr. Alex Jimenez, DC, akupereka: Amayi ambiri amakhala ndi zakudya zopatsa thanzi, kuchita yoga, kuchita nawo zauzimu, ndikucheza ndi anzawo; komabe, pamene milingo yawo ya timadzi tating'onoting'ono, akulimbana ndi zovuta zina zokhudzana ndi kusalinganika kwa HPA kapena adrenal dysfunction. Poyang'ana ntchito ya 24-hour corticotropic ndikuzindikira momwe nyimbo ya circadian imawongolera, madokotala ambiri amatha kuyang'ana deta yomwe imaperekedwa kwa wodwalayo. Momwe deta ikuwonetsedwera kwa wodwala momwe ma hormone awo amasinthira m'thupi m'mawa ndi momwe amadzuka kapena kuchepa tsiku lonse mpaka atagona.
Ndi chidziwitsochi, madokotala ambiri amatha kudziwa chifukwa chake munthuyo akuvutika kugona, kudzuka nthawi zonse usiku, kapena kusapuma mokwanira, zomwe zimapangitsa kuti azikhala otopa tsiku lonse. Ndiye kodi adrenal dysfunction imalumikizidwa bwanji ndi maola 24 a corticotropic? Zinthu zambiri zimatha kuyambitsa kukanika kwa adrenal m'thupi komanso kukhudza kuchuluka kwa mahomoni. Thupi likayamba kuchulukirachulukira kapena kutulutsa mahomoni ochepa kuchokera ku adrenal glands kapena chithokomiro, zimatha kuyambitsa kuchuluka kwa cortisol ndi insulin m'thupi ndikuyambitsa zovuta zosiyanasiyana zomwe zimayambitsa kupweteka kwa minofu ndi mafupa. Nthawi zina kukanika kwa mahomoni kumatha kuyambitsa kupweteka kwa somato-visceral kapena visceral-somatic pokhudza ziwalo zofunika monga matumbo ndi ubongo ndikuyamba kuyambitsa zovuta ku minofu ndi mafupa ozungulira. Pamene minofu ndi ziwalo zozungulira zimabweretsa ululu m'thupi, zimatha kuyambitsa zovuta zomwe zingakhudze mayendedwe a munthu ndikuwapangitsa kukhala omvetsa chisoni.
Momwe Mungadziwire Kusakwanira kwa Adrenal?
Dr. Alex Jimenez, DC, akupereka: Madokotala akazindikira wodwala yemwe ali ndi vuto la adrenal dysfunction ayamba kuyang'ana mbiri yachipatala ya wodwalayo. Odwala ambiri ayamba kulemba mafunso aatali, ochulukirapo, ndipo madotolo ayamba kuyang'ana ma anthropometric, ma biomarkers, ndi zisonyezo zachipatala zomwe zimapezeka pamayeso amthupi. Madokotala ayenera kupeza mbiri ya wodwalayo kuti ayang'ane zizindikiro za kulephera kwa HPA ndi adrenal kukanika kuti adziwe zomwe zimakhudza munthuyo. Pambuyo pofufuza, madokotala amagwiritsa ntchito mankhwala ogwira ntchito kuti ayang'ane komwe kusokonezeka kuli m'thupi komanso momwe zizindikirozo zimagwirizanirana. Zinthu zambiri zomwe zimayambitsa kusagwira bwino ntchito kwa ma adrenal m'thupi zitha kukhala momwe kadyedwe kamunthu kamayambitsa izi, kuchuluka kwa masewera olimbitsa thupi omwe akuchita pamoyo wawo watsiku ndi tsiku, kapena momwe kupsinjika kumamukhudzira.
Mankhwala ogwira ntchito amapereka njira yokhazikika yomwe imaganizira zigawo za moyo zomwe zimayambitsa zovuta m'thupi la munthu. Mwa kulumikiza madontho pazomwe wodwalayo akunena komanso momwe zinthuzi zikupangitsira kusakwanira kwa adrenal, ndikofunikira kuti nkhani yonse ichoke kwa wodwalayo kuti apange dongosolo lamankhwala loperekedwa kwa munthuyo. Iwo angayamikire kuti wina amvetsetsa zomwe akukumana nazo ndipo ayamba kubwezeretsa thanzi lawo ndi thanzi lawo. Poyang'ana zomwe zimayambitsa, zoyambitsa, ndi oyimira pakati omwe amayambitsa vuto la adrenal, titha kuyang'ana mbiri yowonjezereka yomwe wodwalayo akutiuza, kaya ndi mbiri yabanja lawo, zomwe amakonda, kapena zomwe amakonda kuchita kuti asangalale. Zinthu zonsezi ndizofunikira kuziganizira kuyesa ndikulumikiza madontho azomwe zimayambitsa kusakwanira kwa adrenal m'thupi komwe kumakhudza kuchuluka kwa mahomoni amunthu.
Kusakwanira kwa Adrenal Kumakhudza Cortisol
Dr. Alex Jimenez, DC, akupereka: Tsopano, kodi adrenal insufficiencies imagwirizana ndi kuchuluka kwa DHEA ndi ma hormone a cortisol? Chabwino, DHEA ndi mahomoni omwe amapangidwa ndi adrenal glands mwachibadwa. Ntchito yaikulu ya DHEA ndi kupanga mahomoni ena monga estrogen ndi testosterone kuti ayang'anire thupi la mwamuna ndi mkazi. Cortisol ndi mahomoni opsinjika omwe amawonjezera kuchuluka kwa shuga m'magazi. Ntchito yayikulu ya Cortisol ndikulola kuti ubongo ugwiritse ntchito shuga m'thupi ndikukonzanso minofu yomwe yakhudzidwa. Thupi likayamba kuchulukirachulukira kapena kutulutsa mahomoni kuchokera ku adrenal glands, limatha kukweza milingo ya cortisol kuti ipangitse kulimba kwa thupi, ndipo axis ya HPA imayamba kuchepa. Izi zikachitika, thupi limayamba kumva ulesi, zomwe zimatha kukupangitsani kumva kutopa tsiku lonse, ngakhale mutakhala kuti mwagona bwino usiku.
Zizindikiro za Adrenal Insufficiency
Dr. Alex Jimenez, DC, akupereka: Izi zimadziwika kuti adrenal kutopa ndipo zimatha kulumikizidwa ndi zizindikiro zosiyanasiyana zomwe zimakhudza kuchuluka kwa mahomoni m'thupi. Izi zingaphatikizepo zizindikiro zosadziwika bwino monga kusokonezeka kwa tulo, vuto la m'mimba, kutopa, ndi kuwawa kwa thupi kungakhudze kuchuluka kwa mahomoni m'thupi. Izi zimapangitsa kuti anthu ambiri azimva chisoni chifukwa chokhala ndi mphamvu zochepa. Kutopa kwa Adrenal kumathanso kulumikizidwa ndi magawo osiyanasiyana a HPA axis dysfunction. Izi zingaphatikizepo:
Zovuta
Zakudya zosagwirizana ndi zakudya komanso kusamva bwino
Dysbiosis
Kusintha kwa matumbo a microbiota
Toxini
kupanikizika
Insulin kukana
Matenda a zamadzimadzi
Zinthu zonsezi zimatha kukhudza kuchuluka kwa mahomoni amunthu ndikupangitsa kuti cortisol yokwezeka igwirizane ndi zinthu zambiri zomwe zimayambitsa mavuto a somato-visceral. Chitsanzo chingakhale munthu yemwe ali ndi vuto la m'matumbo lomwe limakhudzana ndi kupsinjika kwakanthawi komwe kumatha kumva kuwawa m'malo olumikizirana mafupa awo kuyambira mawondo, m'mbuyo, ndi m'chiuno zomwe zimapangitsa kuti mahomoni awo azisinthasintha.
Dr. Alex Jimenez, DC, akupereka momwe kusokonezeka kwa mahomoni kungayesedwe ndikuchiritsidwa kudzera muzochiritsira zosiyanasiyana zomwe zimagwiritsidwa ntchito ndi mahomoni komanso momwe angawayendetsere mu gawo la 3. Ulalikiwu upereka chidziwitso chofunikira kwa anthu ambiri omwe ali ndi vuto la mahomoni komanso momwe angagwiritsire ntchito njira zosiyanasiyana kuti akwaniritse thanzi lawo komanso thanzi lawo. Gawo 2 liwona kuwunika kwa kusowa kwa mahomoni. Gawo 3 liwona mitundu yosiyanasiyana yamankhwala omwe akupezeka pakukanika kwa mahomoni. Timatumiza odwala kwa othandizira ovomerezeka omwe akuphatikiza mankhwala osiyanasiyana a mahomoni kuti atsimikizire kukhala ndi thanzi labwino komanso thanzi. Timalimbikitsa ndi kuyamikira wodwala aliyense powatumiza kwa azithandizo ogwirizana nawo malinga ndi momwe akudwala pakafunika. Timamvetsetsa kuti maphunziro ndi njira yabwino kwambiri pofunsa opereka athu mafunso ovuta malinga ndi zomwe wodwala akufuna komanso kumvetsetsa kwake. Dr. Alex Jimenez, DC, amangogwiritsa ntchito chidziwitsochi ngati ntchito yophunzitsa. chandalama
Kodi Mahomoni Ndi Chiyani?
Dr. Alex Jimenez, DC, akupereka: Lero, tiwona kugwiritsa ntchito njira zoyambira zothandizira PTSD. Monga njira yochizira, ikukhudza kupanga, mayendedwe, kukhudzika, komanso kutulutsa mahomoni mu PTSD. Chifukwa chake tiyeni tiyambire ndi momwe kulowererapo ndi zinthu zazikulu zomwe zimakhudza njira izi mkati mwa njira zomwe zimakhudzira magawo ena amthupi. Kodi kulowererapo kwa timadzi imodzi kumakhudza bwanji mahomoni ena? Ndiye kodi mumadziwa kuti kusintha kwa chithokomiro kungasinthe mwayi wa HPATG m'thupi? Chifukwa chake anthu akamadwala matenda a hypothyroidism kapena subclinical hyperthyroidism ndipo akuthandizidwa ndi m'malo mwa mahomoni a chithokomiro, zimapangitsa kuti matupi awo asinthe. Izi zikutanthauza kuti adzakhala okhudzidwa kwambiri kuchokera ku ACTH kupita ku CRH kapena mahomoni otulutsa corticotropin.
Izi zikutanthauza kuti apanga ndikutulutsa ACTH yambiri. Wodwalayo akakhala kuti ali ndi hypersensitive chifukwa cha kuchuluka kwa mahomoni, zimatha kuyambitsa zovuta zosiyanasiyana ndi machitidwe ena amthupi omwe amakhudza magwiridwe antchito amthupi ndi minofu. Ichi ndi chifukwa china odwala amamva bwino ngakhale otsika Mlingo wa chithokomiro m'malo; imayambitsa ma adrenals. Odwala ambiri amakonda kuchulukitsa ma adrenals awo, ndipo akalandira chithandizo, amagunda pang'ono ndi ma adrenal awo pomwe madokotala awo amathandizira chithokomiro chawo. Choncho tikayang'ana chithokomiro, timawona kuti chithokomiro chikupanga T4, kupanga reverse T3 ndi T3. Kotero pamene madokotala ayang'ana pa mlingo wa mankhwala a chithokomiro a glucocorticoids, omwe amapereka chithandizo choletsa kutupa kwa odwala awo, kapena ngati anthu akweza glucocorticoids monga matenda a Cushing, zomwe zimachita ndikulepheretsa kutuluka kwa chithokomiro chifukwa chimachepetsa TSH. kuyankha kwa TRH, komwe kumachepetsa TSH. Chithokomiro chikakhala kuti chimatulutsa katulutsidwe kakang'ono kamene kamayambitsa kuchulukirachulukira kokhudzana ndi kunenepa kosafunikira, kupweteka m'malo olumikizirana mafupa, komanso metabolic syndrome.
Kufikira pamenepo, kupsinjika kumalepheretsa chithokomiro. Mosiyana ndi zimenezi, ma estrogens ali ndi zotsatira zosiyana, kumene amachulukitsa katulutsidwe ka TSH ndi ntchito ya chithokomiro. Ndicho chifukwa chake amayi amamva bwino kwambiri ngakhale atakhala ndi mlingo wochepa wa estrogen m'malo. Chifukwa chake, monga momwe chithokomiro chimasinthira m'malo otsika kwambiri chomwe chimagunda ma adrenals, ngati tikupereka Mlingo wochepa wa estrogen, zitha kukulitsa ntchito ya chithokomiro. Komabe, madokotala ambiri amayenera kupita pang'onopang'ono popereka chithandizo cha mahomoni kwa odwala chifukwa mahomoni owonjezera amakhudza mahomoni ena m'thupi. Zikafika pazamankhwala am'malo a mahomoni, ndikofunikira kuphunzira momwe kulowerera mu node yolumikizirana kumakhudzira ma node ena mu matrix. Kotero, mwachitsanzo, tiyeni tiwone momwe node yolumikizirana imakhudzira chitetezo ndi kukonza node m'thupi. Kafukufuku akuwonetsa zotsatira za HRT pa zolembera zotupa ndikuyang'ana azimayi 271 omwe adagwiritsa ntchito conjugated equine estrogen okha, omwe adakwera 121% mu CRP pakatha chaka.
Ndipo ngati adagwiritsa ntchito kuwonjezera pakupanga progestin, anali ndi kuwonjezeka kwa CRP kwa 150% pakatha chaka. Choncho estrogen yopangidwa ndi bioidentical; uwu ndi mkodzo wa mare oyembekezera, ndipo ma progestin opangira amathandizira kutupa. Nanga bwanji njira yolumikizirana ndi ma assimilation node? Ili ndi phunziro losangalatsa chifukwa madokotala ambiri akuyesera kuthandiza odwala awo ndi mbadwo wamtsogolo pakati pa anthu. Chifukwa chake ndikofunikira kudziwa nthawi yomwe mayi ali ndi nkhawa panthawi yomwe ali ndi pakati chifukwa zimatha kusintha microbiome ya mwana. Izi zikutanthauza kuti madokotala ali ndi mwayi wothandizira kulowererapo koyambirira kwa chithandizo cha microbiome. Kudziwa izi ndikofunikira pakupsinjika kwa mwana asanabadwe kutengera mafunso kapena kuchuluka kwa cortisol kumalumikizidwa mwamphamvu komanso mosalekeza ndi ma microbiome a makanda komanso machitidwe atsamunda.
Chifukwa chake tili pano kuti tiphunzire momwe kulowererapo pa matrix kumakhudzira node ya mahomoni kapena njira yolumikizirana. Chifukwa chake mwachitsanzo, tiwona zomwe zimachitika munjira yolumikizirana ndi njira yolumikizirana, chifukwa izi zimakhudza maantibayotiki pamatumbo a metabolome. Aliyense amadziwa za momwe maantibayotiki amakhudzira ma microbiome, koma metabolome ndikusintha kwa kagayidwe kachakudya ka chiwalo china, matumbo. Kufikira pamenepo, pakakhala njira zambiri za kagayidwe kachakudya zomwe maantibayotiki amakhudza, metabolism ya mahomoni a steroid ndiyomwe idakhudzidwa kwambiri. Chifukwa chake ma metabolites asanu ndi atatu omwe ali gawo la njira ya timadzi iyi, yomwe imatipatsa PTSD, idawonjezedwa mu ndowe pambuyo pa chithandizo chamankhwala. Ndiye tili ndi njira ina yomwe matumbo amakhudzira mahomoni, ndipo izi ndikuyang'ana metabolic endotoxemia. Madokotala ambiri amaphunzira za kagayidwe kachakudya endotoxemia mu AFMCP, yomwe imatchula zotuluka m'matumbo kapena kuchuluka kwa matumbo. Pamene anthu ambiri akukumana ndi vuto la m'matumbo lomwe limakhudza thanzi lawo, monga mavuto a m'malo olumikizirana mafupa kapena minofu yomwe imawawawa, timapereka mayankho osiyanasiyana ndikupanga dongosolo lachithandizo ndi othandizira omwe timalumikizana nawo potengera zomwe tapeza.
Endotoxins Zomwe Zimakhudza Ma Hormone
Dr. Alex Jimenez, DC, akupereka: Endotoxins kapena lipopolysaccharides amachokera ku nembanemba yama cell a bakiteriya. Chifukwa chake ma endotoxins a bakiteriya amasamutsidwa kuchokera m'matumbo a lumen chifukwa cha kuchuluka kwa matumbo. Chifukwa chake ndikuwonjezereka kumeneku, ma endotoxins amasamutsidwa, zomwe zimayamba kuphulika. Ma endotoxins akayambitsa zovuta za GI, zolembera zotupa zimatha kukhudza kumtunda ndi kumunsi kwa thupi ndi m'matumbo a ubongo. Pamene m'matumbo-ubongo axis imakhudzidwa ndi kutupa, imatha kubweretsa kupweteka kwamagulu ndi minofu komwe kumakhudzana ndi zovuta za somato-visceral ndi visceral-somatic. Kufikira pamenepo, kutuluka kwa kutupa kochokera m'matumbo otumphukira kumakhudza dzira, kumachepetsa kupanga progesterone, ndipo kumathandizira kuperewera kwa gawo la luteal. Izi ndizofunikira kwambiri kuti madokotala azisamalira odwala omwe alipo kuti azitha kubereka bwino. Ndikofunika kwambiri kuti odwala azidziwitsa madokotala awo akakhala ndi estrogen yowonjezereka komanso kuti akupanga progesterone yochuluka momwe angathere. Chifukwa chake tiyenera kuda nkhawa ndi kufalikira kwa m'matumbo mu ovulation, kuchepa kwa gawo la luteal, komanso kusalinganika kwa estrogen-progesterone. Nanga bwanji za biotransformation node? Kodi izi zimakhudza bwanji njira yolumikizirana? Mu ana a sukulu ya pulayimale, phthalates ndi ntchito ya chithokomiro zimakhala ndi mgwirizano wosiyana pakati pa metabolites kapena kuchuluka kwa folate ndi chithokomiro mu dongosolo loyesedwa mwa ana a zaka zitatu. Pamene nkhani zotupa zimakhudza ntchito ya chithokomiro mwa ana, zimatha kukhudza zotsatira za chidziwitso, motero kuchepetsa kupanga phthalates mu chithokomiro, zomwe zimayambitsa mavuto a maganizo.
Kodi maganizo, maganizo, ndi zinthu zauzimu zimathandiza bwanji kuti muzilankhulana? Tikufuna kuyamba ndi pansi pa matrix monga momwe timachitira nthawi zonse, zomwe zimaphatikizapo mankhwala ogwira ntchito. Mankhwala ogwira ntchito amapereka njira zonse zodziwira vuto lomwe likukhudza thupi ndikupanga dongosolo lamankhwala lamunthu wodwala. Poyang'ana zinthu zamoyo zomwe zili pansi pa Living Matrix, tikhoza kuona momwe kusokonezeka kwa mahomoni kumakhudzira njira zoyankhulirana m'thupi. Pepala laposachedwa lidapeza kuti panali ubale wabwino pakati pazizindikiro zosiya kusamba ndi chithandizo chamagulu komanso kuti chizindikiro chaosiya kusamba chimachepa pomwe chithandizo chamagulu chikuwonjezeka. Tsopano tiyeni tikambirane momwe kupsinjika kumakhudzira kupeza kwa HPA. Poyang'ana momwe kusonkhezera kuchokera ku ziwalo zopanga mahomoni ogonana za thupi kapena zisonga, mwayi wa chithokomiro, ma adrenals, ndi dongosolo lamanjenje lachifundo (nkhondo kapena kuthawa) zingawonjezere zovuta zonse zomwe zimatikhudza, zomwe zimatchedwa allostatic load.
Choncho tisanaganize zopatsa kapena kusintha mahomoni, timafunsa zomwe tingachite kuti tikhudze mahomoniwo m'thupi. Mwachindunji, tingakhudze bwanji kupanga, kuyendetsa, kukhudzidwa, kutulutsa mahomoni, kapena kuchotsa? Ndiye pankhani yopanga mahomoni, ndi chiyani chomwe chimapangira mahomoni a chithokomiro ndi cortisol? Chifukwa chake ngati tili ndi timadzi tating'onoting'ono ta chithokomiro, tikufuna kuwonetsetsa kuti tili ndi zomanga za serotonin. Ndiye chikukhudza kaphatikizidwe? Ngati chithokomiro chapsa ndi autoimmune thyroiditis, sichingathe kupanga mahomoni okwanira a chithokomiro. Ndicho chifukwa chake anthu omwe ali ndi autoimmune thyroiditis amakhala ndi ntchito yochepa ya chithokomiro. Nanga bwanji za kayendedwe ka mahomoni? Kodi kuchuluka kwa timadzi tating'onoting'ono m'thupi kumakhudzanso mlingo wa wina? Estrogen ndi progesterone nthawi zambiri zimakhala mu kuvina m'thupi. Ndiye kodi timadzi timene timatulutsa timadzi timene timatulutsa timadzi tambiri tomwe timapanga timadzi tambiri tomwe timafunikira, zomwe zingakhudze mphamvu yake?
Ngati pali kuchulukitsidwa kwa mahomoni omwe amalumikizidwa ndi puloteni yoyendetsa, sipadzakhala timadzi taulere tokwanira, ndipo pakhoza kukhala zizindikiro za kuchepa kwa timadzi. Kapena zingakhale zosiyana ngati pakufunika kukhala ndi mapuloteni ambiri oyendetsa, ndiye kuti padzakhala mamolekyu ambiri aulere a hormone ndi zizindikiro za mahomoni owonjezera. Choncho, tikufuna kudziwa ngati tingakhudze mlingo wa hormone yaulere ndikuwona ngati ikusinthidwa. Ndiye tikudziwa kuti T4 imakhala mawonekedwe a T3 kapena choletsa chithokomiro, reverse T3, ndipo titha kusintha njirazo? Nanga bwanji sensitivity? Kodi zakudya kapena zakudya zomwe zimathandizira kuyankha kwa ma cell ku cortisol, mahomoni a chithokomiro, testosterone, estrogen, et cetera? Ndi mapuloteni ambiri omwe amamanga ma cell membrane, cell membrane imakhudzidwa ndi metabolism ya mahomoni. Ndipo ngati ma cell membranes ali olimba, insulini, mwachitsanzo, imakhala yovuta kulowamo tsopano pamene tikuyang'ana pakuchotsa mahomoni. Kodi timasintha bwanji metabolism ya estrogens kapena testosterone?
Ndipo tingachite chiyani kuti tikhudze kumanga ndi kutulutsa kwa estrogen? Ndiye, kodi estrogen iyenera kuchotsedwa mwathanzi? Ndipo izi zimatengera ngati pali hydroxylation pa kaboni inayake, komanso imayenera kutulutsidwa malinga ndi kuchuluka kwake. Choncho kudzimbidwa, mwachitsanzo, kudzachepetsa kuchuluka kwa estrogen yotulutsidwa. Chifukwa chake timagwiritsa ntchito chipindacho ngati fanizo komanso mutuwo, monga tidanenera, ndikuchiza matrix poyamba tisanayankhe mwachindunji kusokonekera kwa mahomoni.
Cortisol Imakhudza Ma Node Olankhulana
Dr. Alex Jimenez, DC, akupereka: Mu Living Matrix, tiyenera kumasula kapena kuchiza node zonse kuti titsegule chipinda chosungiramo chipinda kuti tilowe mkati ndi kutulutsa mahomoni. Izi zili choncho chifukwa dongosolo la endocrine ndi lovuta kwambiri moti nthawi zambiri limadziwongolera pamene kusalinganika kwina kumayankhidwa. Ndipo kumbukirani, kusalinganika kwa mahomoni nthawi zambiri ndiko kuyankha koyenera kwa thupi ku kusalinganika kwina. Ndicho chifukwa chake kuchiza kusalinganika kwina nthawi zambiri kumathetsa vuto la mahomoni. Komanso, kumbukirani kuti mahomoni monga piccograms ali otsika kwambiri. Chifukwa chake ndizovuta kunena zolondola tikapatsa odwala mahomoni ndikulola kuti thupi liziwongolera. Ndicho chifukwa chake timati kuchitira matrix poyamba. Ndipo tikalowa mkati mwa njira yolankhulirana m'thupi, timayang'ana pakati pa matrix ndikupeza momwe thupi limakhudzira, malingaliro, ndi ntchito zauzimu kuti tithandizire kukhazikika kwa mahomoni. Ndipo pamene izi zikuyankhidwa, tingakonze bwanji ma hormonal communication node?
Mukakhala mkati mwa node yolumikizirana, mankhwalawa ayenera kutsatira dongosolo: adrenal, chithokomiro, ndi sex steroids. Chifukwa chake awa ndi malingaliro ofunikira kukumbukira, kuchiza ma adrenals, chithokomiro, ndipo pomaliza, ma steroid ogonana. Ndipo njira zomwe tafotokozazi zitha kukhala zogwirizana. Kotero apa mukuwona chiwonetsero chokhazikika chomwe tidzagwiritse ntchito pa njira ya steroidogenic. Ndipo mukuwona mitundu yonse ya mahomoni apa. Ma enzymes omwe ali munjira ya steroidogenic ali ndi mitundu, kotero madokotala ambiri amatha kudziwa kuti ndi enzyme iti yomwe imakhudza gawo liti. Kenaka, tiwona kusintha kwa njira za steroid kupyolera mu moyo, monga masewera olimbitsa thupi, ndi momwe kupanikizika kumakhudzira aromatase, kupanga estrogen.
Tsopano, pamene tikulowa mu gawo lenileni, lolemera pano la njira za steroid, timadziwitsa odwala athu ambiri kuti apume kwambiri monga momwe zikuwonetseratu kuti kupuma kungathe kuonjezera kuzindikira kwa munthu ndikupereka luso lomvetsetsa chirichonse. Chifukwa chake chithunzi chachikulu apa ndikuti chilichonse chimayamba ndi cholesterol komanso momwe zimakhudzira mahomoni m'thupi. Chifukwa chake cholesterol imapanga mineral corticoid aldosterone, yomwe kenako imapanga cortisol, pamapeto pake imapanga androgens ndi estrogens. Odwala akafunsidwa za zomwe zikuchitika ndi matupi awo, ambiri samazindikira kuti cholesterol yokwera imatha kubweretsa kupsinjika kwakanthawi, komwe kumayenderana ndi zovuta zamtima zomwe zimatha kuyambitsa matenda a visceral-somatic.
Kutupa, Insulin, & Cortisol Zomwe Zimakhudza Ma Hormone
Dr. Alex Jimenez, DC, akupereka: Wodwala wachikazi akakumana ndi fibroids kapena endometriosis, madotolo ambiri amapanga njira yochizira ndi othandizira ena kuti achepetse kupangika kwa mahomoni a estrogen poletsa ndikusintha ma enzymes aromatase. Izi zimathandiza wodwala kuti asinthe pang'ono pamayendedwe awo powonetsetsa kuti zinc ake ndi abwinobwino, osamwa zakumwa zoledzeretsa nthawi zonse, kupeza njira zochepetsera kupsinjika kwawo, ndikuwongolera momwe amamwa insulin. Dongosolo lililonse lamankhwala limakhudza munthu akamapeza njira zochepetsera milingo ya cortisol ndikuwongolera kupanga mahomoni athanzi. Izi zidzalola thupi kuonjezera kupanga estrogen pamene kuchepetsa aromatase. Kotero pamene tikukambirana za kupsinjika maganizo, zikhoza kusokoneza njira za hormone mwachindunji mwa kuonjezera cortisol, motero kumapangitsa kuti minyewa ya pituitary iwonjezere CTH pamene nkhawa ikuyankha thupi. Anthu ambiri akukumana ndi kupsinjika kwanthawi yayitali m'matupi awo, zomwe zimatha kuyambitsa mbiri yachiwopsezo pamitsempha yamafupa, zomwe zimayambitsa kupweteka kwa minofu ndi mafupa.
Choncho pituitary system imapanga cortisol pamene thupi limayifuna mwachindunji pamene munthuyo akulimbana ndi kupsyinjika kwakukulu. Komabe, kupsinjika kwakanthawi kumatha kukulitsa milingo ya cortisol mosalunjika; zimapangitsa kuti enzyme 1720 lyase ikhale yoletsedwa m'thupi, kuchititsa kuchepa kwa anabolism, motero kumachepetsa mphamvu za thupi. Chifukwa chake kupsinjika kumalepheretsa enzyme iyi. Chifukwa chake kupsinjika kukalepheretsa 1720 lyase enzyme m'thupi, kumatha kupangitsa kuti pituitary system ipange cortisol yambiri ndikupangitsa kuti zinthu zambiri monga olowa zikhudze munthu. Chifukwa chake izi ndi njira ziwiri zomwe kupsinjika kumatsogolera ku cortisol yochulukira mwachindunji kudzera mu ACTH komanso mwanjira ina poletsa 1720 lyase.
Kutupa ndikofunikira m'thupi chifukwa kumakhalanso ndi njira ziwiri, chifukwa kumatha kukhudza njira izi momwe kupsinjika kumachitikira. Kutupa kumatha kulepheretsa 1720 lyase enzyme, kupangitsa kuti thupi likhale loyambitsa kutupa ndipo limatha kulimbikitsa aromatase. Monga kupsinjika maganizo, pamene thupi likulimbana ndi kutupa, ma cytokines oyambitsa kutupa amalimbikitsa ma enzymes aromatase kuti awonjezere kupanga kwa estrogen. Izi zikachitika, zimalola madokotala kuzindikira chifukwa chake odwala awo amapanikizika kwambiri komanso amakhala ndi zolembera zotupa m'matumbo, minofu, ndi mafupa. Kufikira pamenepo, kutupa kumatha kukulitsa enzyme yotchedwa 5alpha reductase. Tsopano, 5alpha reductase imayambitsa kupanga mahomoni otchedwa dihydrotestosterone (mawonekedwe ogwira ntchito a testosterone m'maselo a thupi osati minofu, kuchititsa tsitsi. Choncho insulini, kupsinjika maganizo, ndi kutupa zimathandizira kutayika tsitsi chifukwa insulini imakhala ndi zotsatira zofanana. kapena shuga wa m'magazi amapatsa thupi mphamvu kuti liziyenda tsiku lonse.Munthu akakhala ndi insulin yochuluka kapena yochepa kwambiri m'thupi, zimatha kuyambitsa kukana kwa insulini, zomwe zimagwirizana ndi kagayidwe kachakudya kamene kamayenderana ndi tsitsi.
Njira Zonse Za Mahomoni
Dr. Alex Jimenez, DC, akupereka: Kodi insulin, cortisol, ndi kutupa zimathandizira bwanji chithokomiro? Chabwino, mahomoni onsewa amathandiza kuti thupi lizigwira ntchito. Chithokomiro chikakhala ndi vuto ngati hypo kapena hyperthyroidism, zimatha kupangitsa kuti thupi lizichulukira kapena kutulutsa timadzi tambiri tomwe timagwira ntchito bwino mthupi. Chifukwa chake kuzungulira kwa chakudya chakutsogoloku kumatha kupangitsa kuti munthu akhale ndi zovuta zosiyanasiyana zomwe zimakhudza thupi lawo chifukwa cha kusokonekera kwa mahomoni. Kuphatikizika kwa insulin kukana, kuchuluka kwa insulin, kunenepa kwambiri, komanso kupsinjika kumakhudza odwala ambiri, zomwe zimayambitsa metabolic syndrome. Kuti tisinthe magwiridwe antchito a mahomoni, tiyenera kuyang'ana pazifukwa zonsezi zomwe zimayendetsa kulephera kwa mahomoni mwa odwala.
Mukapita kukalandira mankhwala a mahomoni, ndikofunikira kudziwa zamitundu yosiyanasiyana yazakudya ndi botanicals chifukwa m'mbuyomu, inkatchedwa kusintha kwa moyo wakale. Mu chipatala chachipatala, neutraceuticals yeniyeni ndi botanicals zingakhudze mapangidwe a estrogen kudzera mu enzyme aromatase. Komabe, zinthu zosiyanasiyana monga matenda, mankhwala, poizoni, komanso kukwera kwa insulin kumatha kuwonjezera ma enzymes aromatase, zomwe zimatsogolera ku estrogen yambiri m'thupi. Ndiyeno matenda, mankhwala, ndi poizoni amachita chinthu chomwecho. Kafukufuku wofufuza akuwonetsa kuti abambo ndi amai akamalumikizana, kuzindikira kwa amuna kumatsika, kenako kumakumana ndi kugonana kosakanizika. Izi zingasinthe momwe timadzi tambiri timagwirira ntchito m'thupi pamene pali kusintha kwa ntchito yovomerezeka yomwe ingakhudze chidziwitso cha ubongo chapakati pa ubongo.
Odwala azaka zapakati akapimidwa ndi madokotala awo, zotsatira zake zimatha kuwonetsa ngati akweza insulini, kuwonjezeka kwa nkhawa komanso ngati pali kutupa m'matupi awo. Izi zimalola madokotala kuti agwire ntchito ndi akatswiri ogwirizana nawo kuti apange dongosolo lamankhwala lomwe limathandizira wodwalayo kuti ayambe kusintha pang'ono paulendo wawo waumoyo ndi thanzi.
